McDonald A J
Division of Emergency Medicine, University of Pittsburgh, Pennsylvania.
Emerg Med Clin North Am. 1989 May;7(2):219-35.
Asthma is an extremely common disease that the emergency physician handles on a daily basis. Accurate clinical assessment from the history and physical examination is very important to assess the severity of the disease. Some measure of airway resistance of either FEV1 or PEFR should be done in every patient initially, at repeated intervals, and at discharge, to have a parameter to follow in therapy as well as a tool to use to warn the physician of a severe amount of airway obstruction. The inhaled beta agonists are the first line of therapy in acute asthma and can be delivered by either the nebulizer or the MDI with or without a spacer. Aminophylline will be continued to be used acutely even though it appears there is no improvement in bronchospasm in the first few hours of treatment when aminophylline is added to therapy. Anticholinergic agents will gain a wider role in acute asthma, especially when used in combination with a beta agonist. Corticosteroids continue to have a role in severe attacks of asthma, and earlier use may prevent relapse. Fatal asthma still occurs, however, and the emergency physician must use strict criteria to recognize status asthmaticus or the patient who is not doing well and admit them to the hospital. Using a stepwise, logical approach to the treatment of the asthmatic patient will lead to better patient satisfaction and fewer errors on part of the emergency physician.
哮喘是急诊医生日常处理的极为常见的疾病。通过病史和体格检查进行准确的临床评估对于评估疾病的严重程度非常重要。每位患者最初、在反复的间隔时间以及出院时都应进行某种测量气道阻力的检查,如第一秒用力呼气容积(FEV1)或呼气峰值流速(PEFR),以便在治疗中有一个可跟踪的参数,同时作为一种工具来警示医生患者存在严重的气道阻塞情况。吸入性β受体激动剂是急性哮喘治疗的一线用药,可通过雾化器或带有或不带有储雾罐的定量吸入器给药。氨茶碱在急性治疗中仍会持续使用,尽管在治疗最初几小时将氨茶碱加入治疗时似乎对支气管痉挛并无改善。抗胆碱能药物在急性哮喘治疗中将发挥更广泛的作用,尤其是与β受体激动剂联合使用时。糖皮质激素在重度哮喘发作中仍发挥作用,早期使用可能预防复发。然而,致命性哮喘仍会发生,急诊医生必须使用严格的标准来识别哮喘持续状态或病情不佳的患者,并将他们收治入院。采用逐步、合理的方法治疗哮喘患者将提高患者满意度,并减少急诊医生的失误。