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直肠癌的局部成像——2015年更新:作为成像生物标志物的MRI

[Local imaging of rectal cancer--update 2015: MRI as imaging biomarker].

作者信息

Schäfer A-O

机构信息

Klinik für Diagnostische und Interventionelle Radiologie, Klinikum St. Georg Leipzig, Delitzscher Straße 141, 04129, Leipzig, Deutschland.

出版信息

Radiologe. 2015 Nov;55(11):1015-26; quiz 1027-8. doi: 10.1007/s00117-015-0030-5.

DOI:10.1007/s00117-015-0030-5
PMID:26538136
Abstract

The significance of state of the art magnetic resonance imaging (MRI) for rectal cancer goes far beyond the detection and diagnostics of local dispersion and is increasingly focusing on patient prognosis. The identification of prognostic factors, such as tumor (T) and nodal (N) status, involvement of the circumferential resection margin, presence of extramural vascular invasion, tumor response prediction following neoadjuvant therapy, therapy-related changes in microcirculation, permeability and tissue cellularity and structured reporting are important elements of advanced rectal cancer imaging. In this context, multiparametric MRI is progressively evolving into a powerful imaging biomarker.

摘要

先进的磁共振成像(MRI)对直肠癌的意义远不止于检测和诊断局部扩散情况,且越来越关注患者的预后。识别预后因素,如肿瘤(T)和淋巴结(N)状态、环周切缘受累情况、壁外血管侵犯的存在、新辅助治疗后肿瘤反应预测、微循环、通透性和组织细胞性的治疗相关变化以及结构化报告,是晚期直肠癌成像的重要要素。在这种背景下,多参数MRI正逐渐发展成为一种强大的成像生物标志物。

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1
[Local imaging of rectal cancer--update 2015: MRI as imaging biomarker].直肠癌的局部成像——2015年更新:作为成像生物标志物的MRI
Radiologe. 2015 Nov;55(11):1015-26; quiz 1027-8. doi: 10.1007/s00117-015-0030-5.
2
Magnetic resonance imaging in rectal cancer.直肠癌的磁共振成像
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3
[Current MRI staging of rectal cancer].[直肠癌的当前MRI分期]
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Eur J Radiol. 2014 Feb;83(2):245-9. doi: 10.1016/j.ejrad.2013.10.029. Epub 2013 Nov 7.
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Magn Reson Imaging Clin N Am. 2013 May;21(2):385-408. doi: 10.1016/j.mric.2013.01.006. Epub 2013 Feb 19.
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Utility of reassessment after neoadjuvant therapy and difficulties in interpretation.新辅助治疗后重新评估的效用及解读困难
Diagn Interv Imaging. 2014 May;95(5):495-503. doi: 10.1016/j.diii.2014.03.010. Epub 2014 Apr 22.
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Accuracy of gadofosveset-enhanced MRI for nodal staging and restaging in rectal cancer.钆塞酸二钠增强 MRI 对直肠癌淋巴结分期和再分期的准确性。
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Neoadjuvant chemotherapy evaluation by MRI volumetry in rectal cancer followed by chemoradiation and total mesorectal excision: Initial experience.直肠癌新辅助化疗后行放化疗和全直肠系膜切除术的 MRI 体绘制评估:初步经验。
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本文引用的文献

1
Combined T2w volumetry, DW-MRI and DCE-MRI for response assessment after neo-adjuvant chemoradiation in locally advanced rectal cancer.联合T2加权容积测量、扩散加权磁共振成像(DW-MRI)和动态对比增强磁共振成像(DCE-MRI)用于局部晚期直肠癌新辅助放化疗后的疗效评估
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Prognostic comparison between mucinous and nonmucinous adenocarcinoma in colorectal cancer.结直肠癌中黏液性腺癌与非黏液性腺癌的预后比较。
Medicine (Baltimore). 2015 Apr;94(15):e658. doi: 10.1097/MD.0000000000000658.
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Adenocarcinoma of the rectum in patients under age 40 is increasing: impact of signet-ring cell histology.
40岁以下患者的直肠腺癌发病率正在上升:印戒细胞组织学的影响。
Dis Colon Rectum. 2015 May;58(5):474-8. doi: 10.1097/DCR.0000000000000318.
4
Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study.低位直肠癌磁共振成像分期系统的前瞻性验证及局部复发风险分层模型的建立:MERCURY II研究
Ann Surg. 2016 Apr;263(4):751-60. doi: 10.1097/SLA.0000000000001193.
5
MRI-detected extramural vascular invasion is an independent prognostic factor for synchronous metastasis in patients with rectal cancer.MRI 检测到的外突血管侵犯是直肠癌患者同步转移的独立预后因素。
Eur Radiol. 2015 May;25(5):1347-55. doi: 10.1007/s00330-014-3527-9. Epub 2014 Dec 13.
6
The prognostic significance of postchemoradiotherapy high-resolution MRI and histopathology detected extramural venous invasion in rectal cancer.放化疗后高分辨率 MRI 与组织病理学检测在直肠癌外突静脉侵犯中的预后意义。
Ann Surg. 2015 Mar;261(3):473-9. doi: 10.1097/SLA.0000000000000848.
7
Pelvic MRI for guiding treatment decisions in rectal cancer.盆腔磁共振成像用于指导直肠癌的治疗决策。
Oncology (Williston Park). 2014 Aug;28(8):667-77.
8
Guiding post-treatment decisions in rectal cancer: mrTRG is a practical place to start.指导直肠癌的治疗后决策:mrTRG是一个切实可行的起点。
Oncology (Williston Park). 2014 Aug;28(8):677-80.
9
Multiparametric MRI of rectal cancer in the assessment of response to therapy: a systematic review.直肠癌治疗反应的多参数 MRI 评估:系统评价。
Dis Colon Rectum. 2014 Jun;57(6):790-9. doi: 10.1097/DCR.0000000000000127.
10
Development and implementation of a synoptic MRI report for preoperative staging of rectal cancer on a population-based level.基于人群的直肠癌术前分期的综合 MRI 报告的制定和实施。
Dis Colon Rectum. 2014 Jun;57(6):700-8. doi: 10.1097/DCR.0000000000000123.