Spadigam Anita, Dhupar Anita, Syed Shaheen, Saluja Tajindra Singh
Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India.
Int J Appl Basic Med Res. 2015 Sep-Dec;5(3):214-6. doi: 10.4103/2229-516X.165367.
Extranodal natural killer/T-cell lymphoma, nasal type (ENKTCL) is a rare Epstein-Barr virus associated lymphoma seen predominantly in Asian population with a 5 years survival rate ranging from 10% to 75% depending on the stage of presentation. In this case report, we describe an unusual presentation of ENKTCL, which in its early stages was clinically misdiagnosed as buccal space infection and later on histologically as inflammatory myofibroblastic pseudotumor owing to manifold reasons. Postoperative biopsy specimen showed characteristic feature of ENKTCL both histologically and immunophenotypically. This case report underlines the importance of adequate sampling and the unusual presentation of ENKTCL nasal type with oral manifestations.
结外自然杀伤/T细胞淋巴瘤，鼻型（ENKTCL）是一种罕见的与EB病毒相关的淋巴瘤，主要见于亚洲人群，其5年生存率根据疾病分期在10%至75%之间。在本病例报告中，我们描述了ENKTCL的一种不寻常表现，由于多种原因，其早期在临床上被误诊为颊间隙感染，后来在组织学上被误诊为炎性肌纤维母细胞性假瘤。术后活检标本在组织学和免疫表型上均显示出ENKTCL的特征性表现。本病例报告强调了充分取材的重要性以及ENKTCL鼻型伴有口腔表现的不寻常表现。
