儿童血清维生素D水平与1型糖尿病的相关性：一项荟萃分析
CORRELATION OF SERUM VITAMIN D LEVEL WITH TYPE 1 DIABETES MELLITUS IN CHILDREN: A META-ANALYSIS.
作者信息
Liu Changwei, Lu Mi, Xia Xiaona, Wang Jingwen, Wan Yuanyuan, He Lianping, Li Mei
机构信息
Nanjing Children's Hospital Affiliated to Nanjing Medical University (Nanjing), Jiangsu..
School of Medical Imaging and laboratory, Wannan Medical College (Wuhu), Anhui..
出版信息
Nutr Hosp. 2015 Oct 1;32(4):1591-4. doi: 10.3305/nh.2015.32.4.9198.
OBJECTIVE
to assess the relationship between serums vitamin D level and type 1 diabetes mellitus (T1DM) in children.
METHODS
the following electronic databases were searched until Sep 2014 to identify relevant studies that assessed the relationship between serum vitamin D with T1DM: PubMed\EMbase\Medline\Central Register of Controlled Trials\CBM\Chinese National Knowledge Infrastructure (CNKI)\wangfang; The NOS scale was used to evaluate the quality of studies, and the statistical tests were performed by Stata 11.0 software.
RESULT
a total of 10 studies were included in this study. Our results showed that serum vitamin D was significantly lower in children with T1DM than in healthy controls (MD = -0.60, P < 0.05). No evidence support publication bias in present study.
CONCLUSION
the meta-analysis suggests that serum vitamin D level is associated with T1DM in children.
目的
评估儿童血清维生素D水平与1型糖尿病（T1DM）之间的关系。
方法
检索以下电子数据库至2014年9月，以识别评估血清维生素D与T1DM之间关系的相关研究：PubMed\EMbase\Medline\对照试验中央注册库\CBM\中国知网（CNKI）\万方；采用NOS量表评估研究质量，统计分析由Stata 11.0软件完成。
结果
本研究共纳入10项研究。结果显示，T1DM患儿的血清维生素D水平显著低于健康对照组（MD = -0.60，P < 0.05）。本研究无证据支持发表偏倚。
结论
荟萃分析表明，儿童血清维生素D水平与T1DM有关。
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