Souza Thompson Motta Rachel, Alves Castanho Ivany, Guillermo Coca Velarde Luis
Brazilian National Cancer Institute José Alencar Gomes da Silva..
Pedro Ernesto University Hospital..
Nutr Hosp. 2015 Nov 1;32(5):2253-60. doi: 10.3305/nh.2015.32.5.9626.
malnutrition is a common complication for cancer patients. The phase angle (PA), direct measurement of bioelectrical impedance analysis (BIA), has been considered a predictor of body cell mass and prognostic indicator. Cutoff points for phase angle (PA) associated with nutritional risk in cancer patients have not been determined yet.
assess the possibility of determining the cutoff point for PA to identify nutritional risk in pre-radiotherapy cancer patients.
sample group: Patients from both genders diagnosed with cancer and sent for ambulatory radiotherapy.
body mass index (BMI), percentage of weight loss (% WL), mid-arm circumference (MAC), triceps skinfold thickness (TST), mid-arm muscle circumference (MAMC), mid-arm muscle area (MAMA), score and categorical assessment obtained using the Patient-Generated Subjective Global Assessment (PG-SGA) form, PA and standardized phase angle (SPA). Kappa coefficient was used to test the degree of agreement between the diagnoses of nutritional risk obtained from several different methods of nutritional assessment. Cutoff points for the PA through anthropometric indicators and PG-SGA were determined by using Receiver Operating Characteristic (ROC) curves, and patient survival was analyzed with the Cox regression method.
the cutoff points with the greatest discriminatory power were those obtained from BMI (5.2) and the categorical assessment of PG-SGA (5.4). The diagnosis obtained using these cutoff points showed a significant association with risk of death for the patients in the sample group.
we recommend using the cutoff point 5.2 for the PA as a criterion for identifying nutritional risk in pre-radiotherapy cancer patients.
营养不良是癌症患者常见的并发症。相位角（PA）是生物电阻抗分析（BIA）的直接测量指标，被认为是身体细胞质量的预测指标和预后指标。尚未确定癌症患者中与营养风险相关的相位角（PA）的截断点。
评估确定PA截断点以识别放疗前癌症患者营养风险的可能性。
样本组：诊断为癌症并接受门诊放疗的男女患者。
体重指数（BMI）、体重减轻百分比（%WL）、上臂中部周长（MAC）、三头肌皮褶厚度（TST）、上臂中部肌肉周长（MAMC）、上臂中部肌肉面积（MAMA）、使用患者主观整体评估（PG-SGA）表格获得的评分和分类评估、PA和标准化相位角（SPA）。使用kappa系数检验通过几种不同营养评估方法获得的营养风险诊断之间的一致程度。通过使用受试者工作特征（ROC）曲线确定通过人体测量指标和PG-SGA得出的PA的截断点，并使用Cox回归方法分析患者生存率。
具有最大判别力的截断点是从BMI（5.2）和PG-SGA的分类评估（5.4）中获得的。使用这些截断点获得的诊断与样本组患者的死亡风险显著相关。
我们建议将PA的截断点5.2用作识别放疗前癌症患者营养风险的标准。
