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2,3,7,8-Tetrachlorodibenzofuran in a commercially available 99% pure polychlorinated biphenyl isomer identified as the inducer of hepatic cytochrome P-448 and aryl hydrocarbon hydroxylase in the rat.

作者信息

Goldstein J A, Hass J R, Linko P, Harvan D J

出版信息

Drug Metab Dispos. 1978 May-Jun;6(3):258-64.

PMID:26546
Abstract
摘要

相似文献

1
2,3,7,8-Tetrachlorodibenzofuran in a commercially available 99% pure polychlorinated biphenyl isomer identified as the inducer of hepatic cytochrome P-448 and aryl hydrocarbon hydroxylase in the rat.在一种市售的99%纯多氯联苯异构体中鉴定出的2,3,7,8-四氯二苯并呋喃，被确定为大鼠肝细胞色素P-448和芳烃羟化酶的诱导剂。
Drug Metab Dispos. 1978 May-Jun;6(3):258-64.
2
2,3,7,8-Tetrachlorodibenzo-p-dioxin induction of aryl hydrocarbon hydroxylase in female rat liver. Evidence for de novo synthesis of cytochrome P-448.2,3,7,8-四氯二苯并-对-二恶英诱导雌性大鼠肝脏芳烃羟化酶。细胞色素P-448从头合成的证据。
Mol Pharmacol. 1978 Sep;14(5):890-9.
3
Inducing potency of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells and mice by polychlorinated dibenzofuran congeners.多氯代二苯并呋喃同系物对人淋巴母细胞和小鼠芳烃羟化酶活性的诱导效力。
Environ Health Perspect. 1985 Feb;59:107-12. doi: 10.1289/ehp.59-1568096.
4
Genetically mediated induction of aryl hydrocarbon hydroxylase activity in mice by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.多氯代二苯并呋喃异构体和2,3,7,8-四氯二苯并对二噁英对小鼠芳烃羟化酶活性的遗传介导诱导作用。
Arch Toxicol. 1985 Feb;56(4):226-9. doi: 10.1007/BF00295158.
5
6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities.6-甲基-1,3,8-三氯二苯并呋喃作为2,3,7,8-四氯二苯并对二噁英拮抗剂：对大鼠细胞色素P-450同工酶诱导及相关单加氧酶活性的抑制作用
Mol Pharmacol. 1988 Feb;33(2):231-6.
6
Comparison of beta-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity.β-萘黄酮与3-甲基胆蒽作为肝细胞色素P-448及芳烃（苯并[a]芘）羟化酶活性诱导剂的比较
Mol Pharmacol. 1977 Mar;13(2):259-68.
7
Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448.基于细胞色素P - 450或P - 448的诱导作用，将纯多氯联苯异构体分为两种诱导剂类型。
Chem Biol Interact. 1977 Apr;17(1):69-87. doi: 10.1016/0009-2797(77)90073-4.
8
Genetically mediated induction of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.多氯代二苯并呋喃异构体和2,3,7,8-四氯二苯并对二噁英对人淋巴母细胞中芳烃羟化酶活性的基因介导诱导作用。
Arch Toxicol. 1985 Feb;56(4):230-5. doi: 10.1007/BF00295159.
9
Effects of chlorinated dibenzofuran and dioxin on concentration and pattern of chlorobiphenyls and activity of benzo(a)pyrene hydroxylation in mice.氯化二苯并呋喃和二噁英对小鼠体内氯代联苯浓度及分布模式以及苯并(a)芘羟基化活性的影响。
Fukuoka Igaku Zasshi. 1985 May;76(5):175-83.
10
[Phenomenon of enzymatic imprinting in adult animals].[成年动物中的酶印记现象]
Biull Eksp Biol Med. 1990 Jun;109(6):546-8.

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Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example.毒物学中合成环境污染物及其（生物）转化产物的鉴定：以多氯联苯为例。
Environ Sci Pollut Res Int. 2018 Jun;25(17):16508-16521. doi: 10.1007/s11356-017-1162-0. Epub 2018 Jan 10.
2
Synthesis of Sterically Hindered Polychlorinated Biphenyl Derivatives.空间位阻多氯联苯衍生物的合成
Synthesis (Stuttg). 2011 Jan 1;7:1045-1054. doi: 10.1055/s-0030-1258454.
3
Development of a synthetic PCB mixture resembling the average polychlorinated biphenyl profile in Chicago air.
合成 PCB 混合物的开发，类似于芝加哥空气中的平均多氯联苯分布。
Environ Int. 2010 Nov;36(8):819-27. doi: 10.1016/j.envint.2009.03.003. Epub 2009 Apr 17.
4
Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites.改进的非二恶英类多氯联苯（PCBs）及其一些含硫代谢物的合成方法。
Environ Int. 2010 Nov;36(8):828-34. doi: 10.1016/j.envint.2009.01.013. Epub 2009 Mar 3.
5
Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones.氯化作用会增加源自多氯联苯对苯二酚和醌的半醌自由基的持久性。
J Org Chem. 2008 Nov 7;73(21):8296-304. doi: 10.1021/jo801397g. Epub 2008 Oct 8.
6
The three-dimensional structure of 3,3',4,4'-tetrachlorobiphenyl, a dioxin-like polychlorinated biphenyl (PCB).二噁英类多氯联苯（PCB）3,3',4,4'-四氯联苯的三维结构
Chemosphere. 2008 Feb;70(9):1694-8. doi: 10.1016/j.chemosphere.2007.07.017. Epub 2007 Aug 27.
7
Effects of polychlorinated biphenyls on liver regeneration in the rat: influence of position and degree of chlorination.多氯联苯对大鼠肝脏再生的影响：氯化位置和程度的影响。
Arch Environ Contam Toxicol. 1982;11(2):239-44. doi: 10.1007/BF01054902.
8
Unmetabolisable polyhalogenated compounds: implications for mammalian and other vertebrate species.不可代谢的多卤代化合物：对哺乳动物及其他脊椎动物物种的影响。
Vet Res Commun. 1983 Dec;7(1-4):277-83. doi: 10.1007/BF02228635.
9
Biochemical and toxicological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) congeners in female rats.
Arch Environ Contam Toxicol. 1987 Sep;16(5):599-605. doi: 10.1007/BF01055816.
10
PCBs: structure-function relationships and mechanism of action.多氯联苯：结构-功能关系及作用机制
Environ Health Perspect. 1985 May;60:47-56. doi: 10.1289/ehp.856047.