在一种市售的99%纯多氯联苯异构体中鉴定出的2,3,7,8-四氯二苯并呋喃，被确定为大鼠肝细胞色素P-448和芳烃羟化酶的诱导剂。 - Suppr

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超能文献

2,3,7,8-Tetrachlorodibenzofuran in a commercially available 99% pure polychlorinated biphenyl isomer identified as the inducer of hepatic cytochrome P-448 and aryl hydrocarbon hydroxylase in the rat.

作者信息

Goldstein J A, Hass J R, Linko P, Harvan D J

出版信息

Drug Metab Dispos. 1978 May-Jun;6(3):258-64.

PMID:26546

Abstract

摘要

相似文献

2,3,7,8-Tetrachlorodibenzofuran in a commercially available 99% pure polychlorinated biphenyl isomer identified as the inducer of hepatic cytochrome P-448 and aryl hydrocarbon hydroxylase in the rat.在一种市售的99%纯多氯联苯异构体中鉴定出的2,3,7,8-四氯二苯并呋喃，被确定为大鼠肝细胞色素P-448和芳烃羟化酶的诱导剂。

Drug Metab Dispos. 1978 May-Jun;6(3):258-64.

2,3,7,8-Tetrachlorodibenzo-p-dioxin induction of aryl hydrocarbon hydroxylase in female rat liver. Evidence for de novo synthesis of cytochrome P-448.2,3,7,8-四氯二苯并-对-二恶英诱导雌性大鼠肝脏芳烃羟化酶。细胞色素P-448从头合成的证据。

Mol Pharmacol. 1978 Sep;14(5):890-9.

Inducing potency of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells and mice by polychlorinated dibenzofuran congeners.多氯代二苯并呋喃同系物对人淋巴母细胞和小鼠芳烃羟化酶活性的诱导效力。

Environ Health Perspect. 1985 Feb;59:107-12. doi: 10.1289/ehp.59-1568096.

Genetically mediated induction of aryl hydrocarbon hydroxylase activity in mice by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.多氯代二苯并呋喃异构体和2,3,7,8-四氯二苯并对二噁英对小鼠芳烃羟化酶活性的遗传介导诱导作用。

Arch Toxicol. 1985 Feb;56(4):226-9. doi: 10.1007/BF00295158.

6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities.6-甲基-1,3,8-三氯二苯并呋喃作为2,3,7,8-四氯二苯并对二噁英拮抗剂：对大鼠细胞色素P-450同工酶诱导及相关单加氧酶活性的抑制作用

Mol Pharmacol. 1988 Feb;33(2):231-6.

Comparison of beta-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity.β-萘黄酮与3-甲基胆蒽作为肝细胞色素P-448及芳烃（苯并[a]芘）羟化酶活性诱导剂的比较

Mol Pharmacol. 1977 Mar;13(2):259-68.

Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448.基于细胞色素P - 450或P - 448的诱导作用，将纯多氯联苯异构体分为两种诱导剂类型。

Chem Biol Interact. 1977 Apr;17(1):69-87. doi: 10.1016/0009-2797(77)90073-4.

Genetically mediated induction of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.多氯代二苯并呋喃异构体和2,3,7,8-四氯二苯并对二噁英对人淋巴母细胞中芳烃羟化酶活性的基因介导诱导作用。

Arch Toxicol. 1985 Feb;56(4):230-5. doi: 10.1007/BF00295159.

Effects of chlorinated dibenzofuran and dioxin on concentration and pattern of chlorobiphenyls and activity of benzo(a)pyrene hydroxylation in mice.氯化二苯并呋喃和二噁英对小鼠体内氯代联苯浓度及分布模式以及苯并(a)芘羟基化活性的影响。

Fukuoka Igaku Zasshi. 1985 May;76(5):175-83.

[Phenomenon of enzymatic imprinting in adult animals].[成年动物中的酶印记现象]

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