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成功实施外倒转术的预测模型:一项系统综述

Prediction models for successful external cephalic version: a systematic review.

作者信息

Velzel Joost, de Hundt Marcella, Mulder Frederique M, Molkenboer Jan F M, Van der Post Joris A M, Mol Ben W, Kok Marjolein

机构信息

Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands.

Department of Obstetrics and Gynaecology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:160-167. doi: 10.1016/j.ejogrb.2015.10.007. Epub 2015 Oct 24.

Abstract

To provide an overview of existing prediction models for successful ECV, and to assess their quality, development and performance. We searched MEDLINE, EMBASE and the Cochrane Library to identify all articles reporting on prediction models for successful ECV published from inception to January 2015. We extracted information on study design, sample size, model-building strategies and validation. We evaluated the phases of model development and summarized their performance in terms of discrimination, calibration and clinical usefulness. We collected different predictor variables together with their defined significance, in order to identify important predictor variables for successful ECV. We identified eight articles reporting on seven prediction models. All models were subjected to internal validation. Only one model was also validated in an external cohort. Two prediction models had a low overall risk of bias, of which only one showed promising predictive performance at internal validation. This model also completed the phase of external validation. For none of the models their impact on clinical practice was evaluated. The most important predictor variables for successful ECV described in the selected articles were parity, placental location, breech engagement and the fetal head being palpable. One model was assessed using discrimination and calibration using internal (AUC 0.71) and external validation (AUC 0.64), while two other models were assessed with discrimination and calibration, respectively. We found one prediction model for breech presentation that was validated in an external cohort and had acceptable predictive performance. This model should be used to council women considering ECV.

摘要

提供现有成功实施外倒转术(ECV)预测模型的概述,并评估其质量、发展情况和性能。我们检索了MEDLINE、EMBASE和Cochrane图书馆,以识别从创刊至2015年1月发表的所有关于成功实施ECV预测模型的文章。我们提取了有关研究设计、样本量、模型构建策略和验证的信息。我们评估了模型开发的阶段,并根据区分度、校准度和临床实用性总结了它们的性能。我们收集了不同的预测变量及其定义的意义,以确定成功实施ECV的重要预测变量。我们确定了八篇报告七个预测模型的文章。所有模型均进行了内部验证。只有一个模型也在外部队列中进行了验证。两个预测模型的总体偏倚风险较低,其中只有一个在内部验证中显示出有前景的预测性能。该模型也完成了外部验证阶段。没有一个模型评估了其对临床实践的影响。所选文章中描述的成功实施ECV的最重要预测变量是产次、胎盘位置、臀先露入盆和可触及胎头。一个模型使用内部(AUC 0.71)和外部验证(AUC 0.64)进行区分度和校准度评估,而另外两个模型分别进行了区分度和校准度评估。我们发现一个用于臀先露的预测模型在外部队列中得到验证,且具有可接受的预测性能。该模型应用于为考虑进行ECV的女性提供咨询。

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