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缓解期双相情感障碍中的夜型偏好及其相关损害

Eveningness and Its Associated Impairments in Remitted Bipolar Disorder.

作者信息

Ng Tommy H, Chung Ka-Fai, Lee Chit-Tat, Yeung Wing-Fai, Ho Fiona Y Y

机构信息

a Department of Psychiatry University of Hong Kong, Hong Kong Special Administrative Region , China.

b Department of Psychiatry Queen Mary Hospital, Hong Kong Special Administrative Region , China.

出版信息

Behav Sleep Med. 2016 Nov-Dec;14(6):650-64. doi: 10.1080/15402002.2015.1065407. Epub 2015 Nov 7.

Abstract

Sleep-wake and circadian rhythm disturbances are common in remitted bipolar disorder. These disturbances include difficulty initiating and maintaining sleep, daytime sleepiness, sleep irregularity, and a circadian tendency toward eveningness. To date, few studies have examined the impact of eveningness on impairments in remitted bipolar disorder. Ninety-eight adults diagnosed with bipolar disorder I, II, or not otherwise specified were evaluated. Hierarchical linear regression analyses showed that eveningness was associated with greater sleep-wake disturbances, more unhealthy dietary habits, worse quality of life, more impaired interpersonal relationships, and more dysfunctional sleep-related cognitions and behaviors, controlling for age, gender, and years of education. Targeted intervention on dysfunctional sleep-related cognitions and behaviors may reverse eveningness and improve functioning in bipolar disorder.

摘要

睡眠-觉醒和昼夜节律紊乱在缓解期双相情感障碍中很常见。这些紊乱包括入睡困难和维持睡眠困难、日间嗜睡、睡眠不规律以及昼夜倾向于晚睡。迄今为止,很少有研究探讨晚睡对缓解期双相情感障碍患者功能损害的影响。对98名被诊断为I型、II型或未另行指定的双相情感障碍的成年人进行了评估。分层线性回归分析表明,在控制年龄、性别和受教育年限后,晚睡与更严重的睡眠-觉醒紊乱、更不健康的饮食习惯、更差的生活质量、受损更严重的人际关系以及更多功能失调的睡眠相关认知和行为有关。针对功能失调的睡眠相关认知和行为进行有针对性的干预可能会扭转晚睡现象,并改善双相情感障碍患者的功能。

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