基因调控与头发颜色：事实还是虚构？
Hair Coloration by Gene Regulation: Fact or Fiction?
机构信息
CEB (Centre of Biological Engineering), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; CBMA (Centre of Molecular and Environmental Biology), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CBMA (Centre of Molecular and Environmental Biology), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
出版信息
Trends Biotechnol. 2015 Dec;33(12):707-711. doi: 10.1016/j.tibtech.2015.10.001. Epub 2015 Nov 5.
The unravelling of hair pigmentation genetics and robust delivery systems to the hair follicle (HF) will allow the development of a new class of colouring products. The challenge will be changing hair colour from inside out by safely regulating the activity of target genes through the specific delivery of synthetic/natural compounds, proteins, genes, or small RNAs.
毛发色素遗传学的研究以及向毛囊（HF）中高效传递系统的建立，将推动新型染发剂的开发。其面临的挑战是通过特定地递呈合成/天然化合物、蛋白质、基因或小 RNA，安全地调控靶基因的活性，从而实现由内而外的变色，达到安全改变头发颜色的目的。
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