Desai Deesha D, Karim Maria, Nohria Ambika, Needle Carli, Brinks Anna, Kearney Caitlin A, Ridge Amy, Mesinkovska Natasha, Shapiro Jerry, Lo Sicco Kristen I
The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY, USA.
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Int J Dermatol. 2025 May;64(5):819-829. doi: 10.1111/ijd.17580. Epub 2024 Dec 19.
Premature hair graying (PHG) is the early loss of natural hair color, influenced by genetic, biological, and environmental factors. This review discusses the significant psychological impacts of PHG and explores its underlying mechanisms, related health conditions, and available treatments. The review examines the roles of genetics, oxidative stress, and lifestyle factors such as smoking and diet in premature graying. It also considers associated medical conditions and current and emerging treatment options. This overview aims to improve understanding of PHG and its broader implications.
早发性白发(PHG)是指自然发色过早丧失,其受遗传、生物和环境因素影响。本综述讨论了早发性白发的重大心理影响,并探讨其潜在机制、相关健康状况及现有治疗方法。该综述研究了遗传、氧化应激以及吸烟和饮食等生活方式因素在早发性白发中的作用。它还考虑了相关的医疗状况以及当前和新兴的治疗选择。本概述旨在增进对早发性白发及其更广泛影响的理解。