Uilenberg G, Franssen F F, Perié N M, Spanjer A A
Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht, The Netherlands.
Vet Q. 1989 Jan;11(1):33-40. doi: 10.1080/01652176.1989.9694194.
Two stocks of large Babesia from dogs originating in France, transmitted by Dermacentor reticulatus, two from North Africa, having Rhipicephalus sanguineus as vector, and one from South Africa, transmitted by Haemaphysalis leachi, were compared in cross-immunity tests in dogs and in the indirect fluorescent antibody test (IFAT). The French and North African stocks did not immunise against the South African one, while the North African stocks did not protect against a French one. The South African stock partially protected against a French one. The three groups could be clearly distinguished in the IFAT. These differences have practical implications for existing and future vaccines against canine babesiosis and for the serological diagnosis of atypical and chronic cases. It is proposed to use a trinomial system of nomenclature for these groups: Babesia canis canis (Piana and Galli-Valerio, 1895), Babesia canis vogeli Reichenow, 1937, and Babesia canis rossi (Nuttall, 1910), having Dermacentor, Rhipicephalus and Haemaphysalis ticks as their vectors respectively.
对源自法国的由网纹革蜱传播的两株大型犬巴贝斯虫、来自北非的以血红扇头蜱为传播媒介的两株巴贝斯虫以及来自南非的由李氏血蜱传播的一株巴贝斯虫，进行了犬的交叉免疫试验和间接荧光抗体试验（IFAT）。法国株和北非株不能使犬对南非株产生免疫，而北非株也不能保护犬抵抗法国株。南非株能部分保护犬抵抗法国株。在间接荧光抗体试验中可以清楚地区分这三组。这些差异对现有的和未来的犬巴贝斯虫疫苗以及非典型和慢性病例的血清学诊断具有实际意义。建议对这些组采用三名法命名系统：犬巴贝斯虫犬亚种（Piana和Galli-Valerio，1895年）、犬巴贝斯虫韦氏亚种Reichenow，1937年和犬巴贝斯虫罗氏亚种（Nuttall，1910年），它们分别以革蜱、扇头蜱和血蜱为传播媒介。
