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与费用相关的处方未取药情况是否与健康状况下降有关?来自一项针对新西兰成年人的大规模纵向研究的结果。

Is cost-related non-collection of prescriptions associated with a reduction in health? Findings from a large-scale longitudinal study of New Zealand adults.

作者信息

Jatrana Santosh, Richardson Ken, Norris Pauline, Crampton Peter

机构信息

Alfred Deakin Institute for Citizenship & Globalisation, Deakin University Waterfront Campus, Geelong, Victoria, Australia.

Department of Public Health, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand.

出版信息

BMJ Open. 2015 Nov 9;5(11):e007781. doi: 10.1136/bmjopen-2015-007781.

Abstract

OBJECTIVE

To investigate whether cost-related non-collection of prescription medication is associated with a decline in health.

SETTINGS

New Zealand Survey of Family, Income and Employment (SoFIE)-Health.

PARTICIPANTS

Data from 17 363 participants with at least two observations in three waves (2004-2005, 2006-2007, 2008-2009) of a panel study were analysed using fixed effects regression modelling.

PRIMARY OUTCOME MEASURES

Self-rated health (SRH), physical health (PCS) and mental health scores (MCS) were the health measures used in this study.

RESULTS

After adjusting for time-varying confounders, non-collection of prescription items was associated with a 0.11 (95% CI 0.07 to 0.15) unit worsening in SRH, a 1.00 (95% CI 0.61 to 1.40) unit decline in PCS and a 1.69 (95% CI 1.19 to 2.18) unit decline in MCS. The interaction of the main exposure with gender was significant for SRH and MCS. Non-collection of prescription items was associated with a decline in SRH of 0.18 (95% CI 0.11 to 0.25) units for males and 0.08 (95% CI 0.03 to 0.13) units for females, and a decrease in MCS of 2.55 (95% CI 1.67 to 3.42) and 1.29 (95% CI 0.70 to 1.89) units for males and females, respectively. The interaction of the main exposure with age was significant for SRH. For respondents aged 15-24 and 25-64 years, non-collection of prescription items was associated with a decline in SRH of 0.12 (95% CI 0.03 to 0.21) and 0.12 (95% CI 0.07 to 0.17) units, respectively, but for respondents aged 65 years and over, non-collection of prescription items had no significant effect on SRH.

CONCLUSION

Our results show that those who do not collect prescription medications because of cost have an increased risk of a subsequent decline in health.

摘要

目的

调查因费用问题未领取处方药是否与健康状况下降有关。

设置

新西兰家庭、收入与就业调查(SoFIE)-健康调查。

参与者

对一项面板研究中17363名参与者在三个调查阶段(2004 - 2005年、2006 - 2007年、2008 - 2009年)至少有两次观测的数据进行固定效应回归建模分析。

主要结局指标

本研究采用的健康指标包括自评健康(SRH)、身体健康评分(PCS)和心理健康评分(MCS)。

结果

在对随时间变化的混杂因素进行调整后,未领取处方药与自评健康状况恶化0.11(95%可信区间0.07至0.15)个单位、身体健康评分下降1.00(95%可信区间0.61至1.40)个单位以及心理健康评分下降1.69(95%可信区间1.19至2.18)个单位相关。主要暴露因素与性别的交互作用在自评健康和心理健康评分方面具有统计学意义。未领取处方药与男性自评健康下降0.18(95%可信区间0.11至0.25)个单位、女性下降0.08(95%可信区间0.03至0.13)个单位相关,与男性心理健康评分下降2.55(95%可信区间1.67至3.42)个单位、女性下降1.29(95%可信区间0.70至1.89)个单位相关。主要暴露因素与年龄的交互作用在自评健康方面具有统计学意义。对于15 - 24岁和25 - 64岁的受访者,未领取处方药分别与自评健康下降0.12(95%可信区间0.03至0.21)个单位和0.12(95%可信区间0.07至0.17)个单位相关,但对于65岁及以上的受访者,未领取处方药对自评健康无显著影响。

结论

我们的结果表明,因费用问题未领取处方药的人群随后健康状况下降的风险增加。

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