Kammermeier Jochen, Morris Mary-Anne, Garrick Vikki, Furman Mark, Rodrigues Astor, Russell Richard K
Institute of Child Health, Great Ormond Street Hospital, London, UK.
Department of Paediatrics, Norfolk and Norwich University Hospital, Norwich, UK.
Arch Dis Child. 2016 May;101(5):475-80. doi: 10.1136/archdischild-2014-307217. Epub 2015 Nov 9.
Crohn's disease (CD) is rapidly increasing in children so an up to date knowledge of diagnosis, investigation and management is essential. Exclusive enteral nutrition is the first line treatment for active disease. The vast majority of children will need immunosuppressant treatment and around 20% will need treatment with biologics. Recent guidelines have helped make best use of available therapies.
克罗恩病(CD)在儿童中的发病率正在迅速上升,因此掌握最新的诊断、检查和治疗知识至关重要。肠内营养是活动性疾病的一线治疗方法。绝大多数儿童需要免疫抑制治疗,约20%的儿童需要生物制剂治疗。最近的指南有助于更好地利用现有疗法。