Azhar Naheed
Department of Anaesthesiology, Stanley Medical College and Government RSRM Hospital, Chennai, Tamil Nadu, India.
Indian J Anaesth. 2015 Sep;59(9):550-6. doi: 10.4103/0019-5049.165858.
The anaesthetic management of patients with pre-existing pulmonary disease is a challenging task. It is associated with increased morbidity in the form of post-operative pulmonary complications. Pre-operative optimisation of lung function helps in reducing these complications. Patients are advised to stop smoking for a period of 4-6 weeks. This reduces airway reactivity, improves mucociliary function and decreases carboxy-haemoglobin. The widely used incentive spirometry may be useful only when combined with other respiratory muscle exercises. Volume-based inspiratory devices have the best results. Pharmacotherapy of asthma and chronic obstructive pulmonary disease must be optimised before considering the patient for elective surgery. Beta 2 agonists, inhaled corticosteroids and systemic corticosteroids, are the main drugs used for this and several drugs play an adjunctive role in medical therapy. A graded approach has been suggested to manage these patients for elective surgery with an aim to achieve optimal pulmonary function.
对已有肺部疾病的患者进行麻醉管理是一项具有挑战性的任务。它与术后肺部并发症形式的发病率增加相关。术前优化肺功能有助于减少这些并发症。建议患者戒烟4至6周。这可降低气道反应性,改善黏液纤毛功能并降低碳氧血红蛋白水平。广泛使用的激励肺活量测定法仅在与其他呼吸肌锻炼相结合时可能有用。基于容量的吸气装置效果最佳。在考虑对患者进行择期手术之前,必须优化哮喘和慢性阻塞性肺疾病的药物治疗。β2受体激动剂、吸入性糖皮质激素和全身性糖皮质激素是用于此目的的主要药物,还有几种药物在药物治疗中起辅助作用。已提出一种分级方法来管理这些择期手术患者,旨在实现最佳肺功能。