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基孔肯雅热患者的精神疾病发病率:来自印度的首次报告。

Psychiatric Morbidity in Patients with Chikungunya Fever: First Report from India.

作者信息

Bhatia M S, Gautam Priyanka, Jhanjee Anurag

机构信息

Professor and Head, Department of Psychiatry, University College of Medical Sciences & Guru Teg Bahadur Hospital , Delhi, India .

Senior Resident, Department of Psychiatry, University College of Medical Sciences & Guru Teg Bahadur Hospital , Delhi, India .

出版信息

J Clin Diagn Res. 2015 Oct;9(10):VC01-VC03. doi: 10.7860/JCDR/2015/14569.6586. Epub 2015 Oct 1.

Abstract

BACKGROUND

Chikungunya fever is an acute illness caused by an arbovirus and has various complications like neurological, psychological, dermatological and even multi organ failure. Psychiatric co-morbidity is not very well studied till now. This is the first report from India.

AIM

Aim of the study was to assess the psychiatric morbidity during or after the onset of Chikungunya fever.

MATERIALS AND METHODS

Patients referred from Medicine department with confirmed diagnosis of Chikungunya fever were recruited, after taking informed consent. Patient's socio-demographic characteristics were noted and Psychiatric co-morbidity was assessed by complete history taking and mental status examination, using WHO International Classification of Diseases, 10(th) edition (ICD -10) of Mental and Behavioural Disorders, Diagnostic criteria for research.

RESULTS

The age range of the study group was found to be 23-48 years. Fourteen (70%) were males and 6 (30%) were females. Five (25%) patients were diagnosed with depressive disorder, 3 (15%) patients had Generalized Anxiety Disorder (GAD), 2 (10%) patients GAD with Panic attacks, 1(5%) patients phobic disorder (claustrophobia), 3 (15%) patients Somatoform Disorder, 3 (15%), Neurasthenia (Fatigue Syndrome), etc. Two (10%) patients presented with vague somatic complaints which did not fit into any of the diagnostic category.

CONCLUSION

Chikungunya fever can result in significant psychiatric morbidity, mainly in the form of depressive episode, anxiety disorder and even long persisting illnesses like somato-form disorders. Further research is required to know about the phenomenology or the neurobiology of the psychiatric disorders occurring in the course of this illness.

摘要

背景

基孔肯雅热是一种由虫媒病毒引起的急性疾病,会引发多种并发症,如神经、心理、皮肤方面的,甚至多器官功能衰竭。到目前为止,对其精神科合并症的研究还不够充分。这是来自印度的首份报告。

目的

本研究旨在评估基孔肯雅热发病期间或之后的精神疾病发病率。

材料与方法

在获得知情同意后,招募了经内科确诊为基孔肯雅热的患者。记录患者的社会人口学特征,并通过完整的病史采集和精神状态检查,依据世界卫生组织《疾病和有关健康问题的国际统计分类》第十版(ICD -10)精神与行为障碍研究诊断标准,评估精神科合并症。

结果

研究组年龄范围为23 - 48岁。男性14名(70%),女性6名(30%)。5名(25%)患者被诊断为抑郁症,3名(15%)患者患有广泛性焦虑障碍(GAD),2名(10%)患者为伴有惊恐发作的GAD,1名(5%)患者患有恐惧症(幽闭恐惧症),3名(15%)患者患有躯体形式障碍,3名(15%)患者患有神经衰弱(疲劳综合征)等。2名(10%)患者出现不符合任何诊断类别的模糊躯体症状。

结论

基孔肯雅热可导致显著的精神疾病发病率,主要表现为抑郁发作、焦虑障碍,甚至是像躯体形式障碍这样持续时间较长的疾病。需要进一步研究以了解在该疾病过程中发生的精神障碍的现象学或神经生物学。

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