Elshal Ahmed M, El-Nahas Ahmed R, Barakat Tamer S, Elsaadany Mohamed M, El-Hefnawy Ahmed S
Mansoura Urology & Nephrology Center, Mansoura University, Egypt.
Arab J Urol. 2013 Dec;11(4):362-8. doi: 10.1016/j.aju.2013.06.003. Epub 2013 Jul 31.
To assess the perioperative morbidity of transvesical open prostatectomy (OP) and its predictors as a treatment for benign prostatic hyperplasia (BPH), and to update knowledge about the morbidity of OP using a standardised morbidity scale (Clavien), thus providing a platform for comparison with the newly developed techniques.
We retrospectively review men with BPH who were treated with transvesical OP between April 2002 and December 2012. Preoperative patients' data were reviewed for relevant variables. Operative details, the postoperative course, and 30-day relevant data were assessed. The study cohort was stratified based on the resected prostate weight, with group 1 having a resected weight of ⩽120 g and group 2 >120 g.
The review identified 163 patients. The mean (SD, range) duration of catheterisation after OP was 7.9 (2.2, 5-20) days and the duration of hospitalisation after OP was 8.1 (1.8, 5-15) days; both were significantly longer in group 2. All patients were able to void spontaneously by the first follow-up visit. Of 163 OP procedures, there were 106 perioperative complications in 69 (42.3%). Low-grade complications (grade ⩽2) included 38 (45.2%) and 53 (67%) in groups 1 and 2, respectively (P = 0.8). High-grade complications (⩾3) included 3 (3.5%) and 12 (15.1%) in groups 1 and 2, respectively (P = 0.02). The blood transfusion rate was 24.5%, the perioperative mortality rate was 1.2% and the re-admission rate within the first 30 days after OP was 1.2%. High-grade complications were significantly associated with a greater resected prostate weight (odds ratio 1.08, 95% CI 1.001-1.17, P = 0.046).
The OP procedure is associated with a significant perioperative morbidity that correlated significantly with the resected prostate weight, especially for high-grade complications.
评估经膀胱开放性前列腺切除术(OP)治疗良性前列腺增生(BPH)的围手术期发病率及其预测因素,并使用标准化发病率量表(Clavien)更新有关OP发病率的知识,从而为与新开发技术进行比较提供一个平台。
我们回顾性分析了2002年4月至2012年12月期间接受经膀胱OP治疗的BPH男性患者。对术前患者数据进行相关变量审查。评估手术细节、术后病程和30天相关数据。研究队列根据切除的前列腺重量分层,第1组切除重量≤120 g,第2组>120 g。
该回顾共纳入163例患者。OP术后平均(标准差,范围)导尿时间为7.9(2.2,5 - 20)天,OP术后住院时间为8.1(1.8,5 - 15)天;第2组两者均显著更长。所有患者在首次随访时均能自主排尿。在163例OP手术中,69例(42.3%)出现106例围手术期并发症。低级别并发症(≤2级)在第1组和第2组中分别为38例(45.2%)和53例(67%)(P = 0.8)。高级别并发症(≥3级)在第1组和第2组中分别为3例(3.5%)和12例(15.1%)(P = 0.02)。输血率为24.5%,围手术期死亡率为1.2%,OP后前30天内再入院率为1.2%。高级别并发症与更大的切除前列腺重量显著相关(比值比1.08,95%可信区间1.001 - 1.17,P = 0.046)。
OP手术与显著的围手术期发病率相关,且与切除的前列腺重量显著相关,尤其是高级别并发症。