Gorkem Umit, Gungor Tayfun, Bas Yılmaz, Togrul Cihan
Department of Obstetrics and Gynecology, Hitit University Faculty of Medicine, 19040 Çorum, Turkey.
Department of Pathology, Hitit University Hospital, 19040 Çorum, Turkey.
Case Rep Obstet Gynecol. 2015;2015:263945. doi: 10.1155/2015/263945. Epub 2015 Oct 8.
Sarcoidosis is a multisystem inflammatory disorder of unknown etiology. It shows a great variety of clinical presentation, organ involvement, and disease progression. Lungs and lymphoid system are the most common sites involved with a frequency of 90% and 30%, respectively. Extrapulmonary involvement of sarcoidosis is reported in 30% of patients and abdomen is the most frequent site. Furthermore, peritoneal involvement is extremely rare in sarcoidosis. The case presented here described peritoneal manifestations of sarcoidosis without involvement of lungs. A 78-year-old woman possessing signs of malignancy on blood test and abdominal magnetic resonance imaging underwent laparatomy with a suspicion of ovarian malignancy. The macroscopic interpretation during surgery was peritoneal carcinomatosis. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, peritoneal biopsies, total omentectomy, and appendectomy were performed. Final histopathological result revealed the diagnosis of sarcoidosis. Clinicians must keep in mind that peritoneal sarcoidosis can mimic intra-abdominal malignancies.
结节病是一种病因不明的多系统炎症性疾病。它表现出多种多样的临床表现、器官受累情况及疾病进展。肺和淋巴系统是最常受累的部位,受累频率分别为90%和30%。30%的结节病患者有肺外受累情况,腹部是最常见的受累部位。此外,结节病累及腹膜极为罕见。本文报道的病例描述了结节病的腹膜表现,而肺部未受累。一名78岁女性,血液检查和腹部磁共振成像显示有恶性肿瘤迹象,因怀疑卵巢恶性肿瘤而接受剖腹手术。手术中的宏观判断为腹膜癌转移。进行了全腹子宫切除术、双侧输卵管卵巢切除术、腹膜活检、全网膜切除术和阑尾切除术。最终组织病理学结果显示为结节病。临床医生必须牢记,腹膜结节病可酷似腹内恶性肿瘤。