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使用肉毒杆菌毒素注射治疗外周刺激器诱发的面部肌肉抽搐:一例报告。

Use of botulinum toxin injections to treat peripheral stimulator induced facial muscle twitching: a case report.

作者信息

Trentman Terrence L, Maloney Jillian A, Wie Christopher S, Rebecca Alanna M, Rosenfeld David M

机构信息

Department of Anesthesiology and Pain Medicine, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054 USA.

Valley Pain Consultants, Phoenix, AZ USA.

出版信息

Springerplus. 2015 Nov 4;4:671. doi: 10.1186/s40064-015-1473-x. eCollection 2015.

Abstract

BACKGROUND

Facial pain can be a management challenge. Peripheral nerve/field stimulation may be an effective option for refractory cases, but direct muscle stimulation with facial twitching may result. Botulinum toxin injections have been used for blepharospasm and may be effective when facial stimulation results in unacceptable facial muscle twitching due to peripheral stimulation.

CASE PRESENTATION

A 53-year old female suffered with chronic, refractory facial pain and migraines. Her facial pain began after a root canal of a left upper molar. She was trialed and then permanently implanted with a 1 × 8 sub-compact percutaneous stimulator lead, resulting in improved pain control and reduced medication use. However, she experienced blepharospasm whenever the amplitude was above 2.75 A. Therefore, she was treated with botulinum toxin injections into her bilateral cheek, face, temple and occiput. This treatment provided excellent relief of the facial spasms, allowing her to use her stimulator at high amplitudes, and thereby maximizing her pain relief. She received two subsequent treatments of botulinum toxin injections at 5-month intervals with similar results.

CONCLUSION

Peripheral nerve/field stimulation is being used for headaches and facial pain. An undesirable side effect of this emerging therapy is direct muscle stimulation. Botulinum toxin injections may be an effective treatment modality when stimulation techniques provide pain relief but also causes muscle twitching.

摘要

背景

面部疼痛可能是一个治疗难题。周围神经/区域刺激对于难治性病例可能是一种有效的选择,但可能会导致面部抽搐的直接肌肉刺激。肉毒杆菌毒素注射已用于治疗眼睑痉挛,当由于周围刺激导致面部刺激引起不可接受的面部肌肉抽搐时可能有效。

病例介绍

一名53岁女性患有慢性难治性面部疼痛和偏头痛。她的面部疼痛始于左上磨牙根管治疗后。她先进行了试验性治疗,然后永久性植入了一根1×8紧凑型经皮刺激器导线,疼痛得到改善,用药量减少。然而,每当振幅超过2.75安培时,她就会出现眼睑痉挛。因此,对她双侧脸颊、面部、颞部和枕部进行了肉毒杆菌毒素注射治疗。这种治疗极大地缓解了面部痉挛,使她能够在高振幅下使用刺激器,从而最大限度地缓解疼痛。随后她每隔5个月接受了两次肉毒杆菌毒素注射治疗,结果相似。

结论

周围神经/区域刺激正用于治疗头痛和面部疼痛。这种新兴疗法的一个不良副作用是直接肌肉刺激。当刺激技术缓解疼痛但也引起肌肉抽搐时,肉毒杆菌毒素注射可能是一种有效的治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381e/4633430/efb9e864b2b1/40064_2015_1473_Fig1_HTML.jpg

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