Mack Molly, Gopal Ambarish
Cardiopulmonary Research Science and Technology Institute (CRSTI), 7777 Forest Lane, C-742, Dallas, TX 75230, USA.
The Heart Hospital Baylor Plano, 1100 Allied Drive, Plano, TX 75093, USA.
Heart Fail Clin. 2016 Jan;12(1):1-10. doi: 10.1016/j.hfc.2015.08.002.
Coronary artery disease (CAD) mortality has been declining in the United States and in regions where health care systems are relatively advanced. Still, CAD remains the number one cause of death in both men and women in the United States, and coronary events have increased in women. Many traditional risk factors for CAD are related to lifestyle, and preventative treatment can be tailored to modifying specific factors. Novel risk factors also may contribute to CAD. Finally, as the risk for CAD is largely understood to be inherited, further genetic testing should play a role in preventative treatment of the disease.
在美国以及医疗保健系统相对先进的地区，冠心病（CAD）死亡率一直在下降。尽管如此，CAD在美国男性和女性中仍然是首要死因，而且女性的冠心病事件有所增加。CAD的许多传统风险因素与生活方式有关，预防性治疗可以针对特定因素进行调整。新的风险因素也可能导致CAD。最后，由于人们普遍认为CAD风险具有遗传性，进一步的基因检测应该在该疾病的预防性治疗中发挥作用。
