Wu Jie, Wu Hong, Wang Juan, Guo Lan, Deng Xueqing, Lu Ciyong
School of Public Health, Sun Yat-sen University, Department of Medical Statistics and Epidemiology Guangzhou, 510080 China.
UCLA Fielding School of Public Health, University of California Los Angeles, Department of Epidemiology, Los Angeles, 90066 United States of America.
Sci Rep. 2015 Nov 16;5:16686. doi: 10.1038/srep16686.
The findings about the shapes of associations between sleep duration and overweight/obesity in adolescents were largely inconsistent in the existing literature. We examined the functional forms of the associations between sleep duration and overweight/obesity in 66,817 Chinese adolescents by modelling sleep duration categorically and continuously. The adjusted ORs (95% CI) of overweight (with 7.0-8.9 h of sleep being considered the reference group) for subjects reporting <5.0 hours, 5.0-6.9 hours and ≥9.0 hours of sleep were 1.26 (1.05-1.51), 1.06 (1.00-1.11) and 1.27 (1.14-1.42), respectively. The adjusted ORs (95% CI) of obesity (with 7.0-8.9 h of daily sleep being considered as the reference group) for adolescents reporting <5.0 hours, 5.0-6.9 hours and ≥9.0 hours of sleep were 1.24 (0.97-1.57), 0.94 (0.87-1.01) and 1.42 (1.24-1.63), respectively. Continuous splines regressions support non-linear U shape associations between sleep duration and overweight/obesity, with the bottom at around 7.0-8.0 hours sleep (overweight: likelihood ratio = 32.7 p < 0.01; obesity: likelihood ratio = 40.4 p < 0.01). U-shape associations were found between sleep duration and overweight/obesity in Chinese adolescents and an optimal sleep duration of 7.0-8.0 hours sleep may prevent overweight/obesity.
在现有文献中，关于青少年睡眠时间与超重/肥胖之间关联的形状的研究结果在很大程度上并不一致。我们通过对睡眠时间进行分类和连续建模，研究了66817名中国青少年睡眠时间与超重/肥胖之间关联的函数形式。报告睡眠时间<5.0小时、5.0 - 6.9小时和≥9.0小时的受试者超重的校正比值比（95%置信区间）（以7.0 - 8.9小时睡眠为参照组）分别为1.26（1.05 - 1.51）、1.06（1.00 - 1.11）和1.27（1.14 - 1.42）。报告睡眠时间<5.0小时、5.0 - 6.9小时和≥9.0小时的青少年肥胖的校正比值比（95%置信区间）（以每天7.0 - 8.9小时睡眠为参照组）分别为1.24（0.97 - 1.57）、0.94（0.87 - 1.01）和1.42（1.24 - 1.63）。连续样条回归支持睡眠时间与超重/肥胖之间呈非线性U形关联，最低点在睡眠约7.0 - 8.0小时处（超重：似然比 = 32.7，p < 0.01；肥胖：似然比 = 40.4，p < 0.01）。在中国青少年中发现睡眠时间与超重/肥胖之间存在U形关联，最佳睡眠时间为7.0 - 8.0小时可能预防超重/肥胖。
