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远端脾肾分流术与脾肾分流术治疗急性静脉曲张出血:选择性分流术是一种进步吗?

Distal splenorenal versus lienorenal shunt for acute variceal haemorrhage: is the selective shunt an advance?

作者信息

Lodge J P, Mavor A I, Giles G R

出版信息

J R Coll Surg Edinb. 1989 Apr;34(2):59-62.

PMID:2657041
Abstract

Retrospective analysis of 81 patients (average age 48 years) undergoing lienorenal shunt (28) or distal splenorenal (Warren) shunt (53) surgery over a 15-year period (1971-1986) revealed important predictive factors for survival, but showed no significant differences between the two shunt groups in terms of accepted follow-up data over a period of up to 15 years. In 52 patients (64%) active haemorrhage was occurring at the time of operation, or was temporarily controlled by tamponade, and 17 of the 18 deaths (22% operative mortality) occurred in this group. Patients in whom prolonged conservative resuscitation had been attempted fared worse (64% survival), as did patients with poor hepatic reserve (Pugh grade C: 32% survival). Twenty-two patients (27%) rebled within 30 days, 18 following urgent shunts, and 12 died. Seven (11%) of the long-term survivors have suffered recurrent variceal haemorrhage with a clear relationship to shunt or portal system thrombosis. Portasystemic encephalopathy occurred in 13 survivors (20%) with six requiring hospital treatment.

摘要

对1971年至1986年这15年间接受脾肾分流术(28例)或远端脾肾(沃伦)分流术(53例)的81例患者(平均年龄48岁)进行回顾性分析,发现了重要的生存预测因素,但在长达15年的可接受随访数据方面,两组分流术之间没有显著差异。52例患者(64%)在手术时发生活动性出血,或通过填塞暂时得到控制,18例死亡患者中有17例(手术死亡率22%)发生在该组。尝试进行长时间保守复苏的患者预后较差(生存率64%),肝储备功能差的患者(普格C级:生存率32%)也是如此。22例患者(27%)在30天内再次出血,18例在紧急分流术后出血,12例死亡。7例(11%)长期存活者发生复发性静脉曲张出血,与分流或门静脉系统血栓形成有明确关系。13例幸存者(20%)发生门体性脑病,其中6例需要住院治疗。

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引用本文的文献

1
Surgical management of acute variceal hemorrhage.急性静脉曲张出血的外科治疗
World J Surg. 1994 Mar-Apr;18(2):193-9. doi: 10.1007/BF00294400.