Sachs Christoph, Lehnhardt Marcus, Daigeler Adrien, Goertz Ole
Clinic for Plastic Surgery and Severe Burn Injuries, Hand Surgery Center, Operative Sarcoma Reference Center, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum.
Dtsch Arztebl Int. 2015 Oct 30;112(44):741-7. doi: 10.3238/arztebl.2015.0741.
In Central Europe, cold-induced injuries are much less common than burns. In a burn center in western Germany, the mean ratio of these two types of injury over the past 10 years was 1 to 35. Because cold-induced injuries are so rare, physicians often do not know how to deal with them.
This article is based on a review of publications (up to December 2014) retrieved by a selective search in PubMed using the terms "freezing," "frostbite injury," "non-freezing cold injury," and "frostbite review," as well as on the authors' clinical experience.
Freezing and cold-induced trauma are part of the treatment spectrum in burn centers. The treatment of cold-induced injuries is not standardized and is based largely on case reports and observations of use. distinction is drawn between non-freezing injuries, in which there is a slow temperature drop in tissue without freezing, and freezing injuries in which ice crystals form in tissue. In all cases of cold-induced injury, the patient should be slowly warmed to 22°-27°C to prevent reperfusion injury. Freezing injuries are treated with warming of the body's core temperature and with the bathing of the affected body parts in warm water with added antiseptic agents. Any large or open vesicles that are already apparent should be debrided. To inhibit prostaglandin-mediated thrombosis, ibuprofen is given (12 mg/kg body weight b.i.d.).
The treatment of cold-induced injuries is based on their type, severity, and timing. The recommendations above are grade C recommendations. The current approach to reperfusion has yielded promising initial results and should be further investigated in prospective studies.
在中欧,寒冷导致的损伤比烧伤少见得多。在德国西部的一家烧伤中心,过去10年这两种损伤的平均比例为1比35。由于寒冷导致的损伤非常罕见,医生们常常不知道如何处理。
本文基于对通过在PubMed中使用“冻伤”“冻伤损伤”“非冻伤性冷损伤”和“冻伤综述”等术语进行选择性检索所获取的出版物(截至2014年12月)的回顾,以及作者的临床经验。
冻伤和寒冷导致的创伤属于烧伤中心的治疗范畴。寒冷导致损伤的治疗并不规范,很大程度上基于病例报告和使用观察。区分了非冻伤性损伤(组织温度缓慢下降但未冻伤)和冻伤性损伤(组织中形成冰晶)。在所有寒冷导致损伤的病例中,应将患者缓慢复温至22°C - 27°C以防止再灌注损伤。冻伤性损伤的治疗方法是使身体核心温度升高,并将受影响的身体部位浸泡在添加了抗菌剂的温水中。任何已经出现的大水泡或开放性水泡都应进行清创处理。为抑制前列腺素介导的血栓形成,给予布洛芬(12毫克/千克体重,每日两次)。
寒冷导致损伤的治疗基于其类型、严重程度和时机。上述建议为C级建议。目前的再灌注方法已取得了有前景的初步结果,应在前瞻性研究中进一步探究。