Wennergren John Emil, Askenasy Erik P, Greenberg Jacob A, Holihan Julie, Keith Jerrod, Liang Mike K, Martindale Robert G, Trott Skylar, Plymale Margaret, Roth John Scott
Department of Surgery, University of Kentucky, C-225 Chandler Medical Center, 800 Rose Street, Lexington, KY, 40536, USA.
Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Surg Endosc. 2016 Aug;30(8):3231-8. doi: 10.1007/s00464-015-4644-5. Epub 2015 Nov 17.
Laparoscopy, specifically the bridged mesh technique, is a popular means used for ventral hernia repair. While laparoscopy has decreased the incidence of surgical site infection (SSI), hernia recurrence rates remain unchanged. Some surgeons advocate laparoscopic primary fascial closure (PFC) with placement of intraperitoneal mesh to decrease recurrence rates. We hypothesize that in patients undergoing laparoscopic ventral hernia repair (LVHR), PFC compared to a bridged mesh repair decreases hernia recurrence rates.
A multicenter, retrospective database of all ventral hernia repairs performed from 2010-2012 was accessed. Patients who underwent LVHR with mesh were reviewed. Patients who had PFC were compared to bridged repair. Primary outcome was hernia recurrence determined by clinical examination or CT scan. Secondary outcomes included SSI and seroma formation.
A total of 1594 patients were identified. Following exclusion, a total of 196 patients were left who underwent LVHR with a mean follow-up period of 17.5 months. Ninety-seven patients underwent PFC, while 99 underwent bridged repairs. Initial comparisons between both groups was negative for any significant statistical difference in terms of recurrence, seroma formation, SSI, deep/organ space SSI, reoperation, and readmission. The same initial findings held true during subgroup analysis. Propensity score analysis was then performed for recurrence, seroma, and SSI controlling for age, gender, immune status, ASA class, BMI, smoking status, and acute repair. No statistically significant differences were identified in either group.
Primary fascial closure during laparoscopic hernia repairs did not result in reduced recurrence, seroma, and SSI as compared to bridge repairs in a retrospective, multi-institutional study. However, additional research is needed to further evaluate benefits to the patient in terms of pain, function, cosmesis, and overall satisfaction. Randomized, blinded, control trials should focus on these parameters in future investigations.
腹腔镜检查,特别是桥接补片技术,是用于腹疝修补的一种常用方法。虽然腹腔镜检查降低了手术部位感染(SSI)的发生率,但疝复发率仍未改变。一些外科医生主张采用腹腔镜下一期筋膜闭合(PFC)并放置腹膜内补片以降低复发率。我们假设,在接受腹腔镜腹疝修补术(LVHR)的患者中,与桥接补片修补相比,PFC可降低疝复发率。
访问了一个多中心回顾性数据库,该数据库涵盖了2010年至2012年期间进行的所有腹疝修补手术。对接受带补片LVHR的患者进行了评估。将接受PFC的患者与桥接修补患者进行比较。主要结局是通过临床检查或CT扫描确定的疝复发。次要结局包括SSI和血清肿形成。
共识别出1594例患者。排除后,共有196例患者接受了LVHR,平均随访期为17.5个月。97例患者接受了PFC,而99例接受了桥接修补。两组之间在复发、血清肿形成、SSI、深部/器官间隙SSI、再次手术和再次入院方面的任何显著统计学差异的初步比较均为阴性。在亚组分析中,相同的初步结果仍然成立。然后针对复发、血清肿和SSI进行倾向评分分析,对年龄、性别、免疫状态、ASA分级、BMI、吸烟状态和急诊修补进行了控制。两组均未发现统计学上的显著差异。
在一项回顾性多机构研究中,与桥接修补相比,腹腔镜疝修补术中的一期筋膜闭合并未降低复发、血清肿和SSI的发生率。然而,需要进一步研究以在疼痛、功能、美容和总体满意度方面进一步评估对患者的益处。未来的研究中,随机、盲法对照试验应关注这些参数。