E F Graves Lee, C Murphy Rebecca, Shepherd Sam O, Cabot Josephine, Hopkins Nicola D
Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK.
Research Institute for Sport and Exercise Science, Physical Activity Exchange, Liverpool John Moores University, 62 Great Crosshall Street, Liverpool, L3 2AT, UK.
BMC Public Health. 2015 Nov 19;15:1145. doi: 10.1186/s12889-015-2469-8.
Excessive sitting time is a risk factor for cardiovascular disease mortality and morbidity independent of physical activity. This aim of this study was to evaluate the impact of a sit-stand workstation on sitting time, and vascular, metabolic and musculoskeletal outcomes in office workers, and to investigate workstation acceptability and feasibility.
A two-arm, parallel-group, individually randomised controlled trial was conducted in one organisation. Participants were asymptomatic full-time office workers aged ≥18 years. Each participant in the intervention arm had a sit-stand workstation installed on their workplace desk for 8 weeks. Participants in the control arm received no intervention. The primary outcome was workplace sitting time, assessed at 0, 4 and 8 weeks by an ecological momentary assessment diary. Secondary behavioural, cardiometabolic and musculoskeletal outcomes were assessed. Acceptability and feasibility were assessed via questionnaire and interview. ANCOVA and magnitude-based inferences examined intervention effects relative to controls at 4 and 8 weeks. Participants and researchers were not blind to group allocation.
Forty-seven participants were randomised (intervention n = 26; control n = 21). Relative to the control group at 8 weeks, the intervention group had a beneficial decrease in sitting time (-80.2 min/8-h workday (95 % CI = -129.0, -31.4); p = 0.002), increase in standing time (72.9 min/8-h workday (21.2, 124.6); p = 0.007) and decrease in total cholesterol (-0.40 mmol/L (-0.79, -0.003); p = 0.049). No harmful changes in musculoskeletal discomfort/pain were observed relative to controls, and beneficial changes in flow-mediated dilation and diastolic blood pressure were observed. Most participants self-reported that the workstation was easy to use and their work-related productivity did not decrease when using the device. Factors that negatively influenced workstation use were workstation design, the social environment, work tasks and habits.
Short-term use of a feasible sit-stand workstation reduced daily sitting time and led to beneficial improvements in cardiometabolic risk parameters in asymptomatic office workers. These findings imply that if the observed use of the sit-stand workstations continued over a longer duration, sit-stand workstations may have important ramifications for the prevention and reduction of cardiometabolic risk in a large proportion of the working population.
ClinicalTrials.gov NCT02496507 .
久坐时间是心血管疾病死亡率和发病率的一个风险因素,与身体活动无关。本研究的目的是评估坐站两用工作站对上班族久坐时间、血管、代谢和肌肉骨骼指标的影响,并调查工作站的可接受性和可行性。
在一个机构中进行了一项双臂、平行组、个体随机对照试验。参与者为年龄≥18岁的无症状全职上班族。干预组的每位参与者在其工作台上安装一个坐站两用工作站,为期8周。对照组的参与者不接受干预。主要结局是工作场所的久坐时间,通过生态瞬时评估日记在0、4和8周时进行评估。对次要行为、心脏代谢和肌肉骨骼结局进行评估。通过问卷调查和访谈评估可接受性和可行性。采用协方差分析和基于效应量的推断方法,在4周和8周时检查干预组相对于对照组的效应。参与者和研究人员知晓分组情况。
47名参与者被随机分组(干预组n = 26;对照组n = 21)。与8周时的对照组相比,干预组的久坐时间有有益的减少(-80.2分钟/8小时工作日(95%CI = -129.0,-31.4);p = 0.002),站立时间增加(72.9分钟/8小时工作日(21.2,124.6);p = 0.007),总胆固醇降低(-0.40毫摩尔/升(-0.79,-0.003);p = 0.049)。相对于对照组,未观察到肌肉骨骼不适/疼痛的有害变化,并且观察到血流介导的血管舒张和舒张压有有益变化。大多数参与者自我报告称该工作站易于使用,并且使用该设备时他们与工作相关的生产力没有下降。对工作站使用产生负面影响的因素包括工作站设计、社交环境、工作任务和习惯。
短期使用可行的坐站两用工作站可减少每日久坐时间,并使无症状上班族的心脏代谢风险参数得到有益改善。这些发现意味着,如果观察到的坐站两用工作站的使用持续更长时间,坐站两用工作站可能对很大一部分工作人群预防和降低心脏代谢风险具有重要意义。
ClinicalTrials.gov NCT02496507 。