Department of Movement Sciences, University of Idaho, 875 Perimeter Drive, MS 2401, Moscow, ID, 83844-2401, USA.
Eur J Appl Physiol. 2014 May;114(5):907-19. doi: 10.1007/s00421-014-2822-0. Epub 2014 Jan 28.
To investigate the associations among objectively measured sedentary behavior, light physical activity, and markers of cardiometabolic health in young women.
Cardiovascular disease risk factors, homeostasis model assessment for insulin resistance (HOMA-IR), lipid accumulation product, and inflammatory markers were measured in 50 young, adult women. Accelerometers were worn over 7 days to assess sedentary time (<150 counts min(-1)), light physical activity (150-2,689 counts min(-1)), and moderate-to-vigorous physical activity (MVPA; ≥2,690 counts min(-1)). Multivariate regression examined independent associations of sedentary behavior and light physical activity with cardiometabolic health. Covariates included MVPA, cardiorespiratory fitness (VO2peak) and body mass, and body composition.
Sedentary behavior was associated with triglycerides (p = 0.03) and lipid accumulation product (p = 0.02) independent of MVPA. These associations were attenuated by VO2peak and body mass or body composition (p ≥ 0.05). Light physical activity was independently associated with triglycerides and lipid accumulation product after adjustment for all covariates (p < 0.05). The association between light physical activity and HOMA-IR was independent of MVPA (p = 0.02) but was attenuated by VO2peak and body mass or body composition (p > 0.05).
Sedentary behavior and light physical activity were independently associated with markers of cardiometabolic health in young, adult women. Our data suggest that VO2peak and body composition may be important mediators of these associations. Decreasing sedentary behavior and increasing light physical activity may be important for maintaining cardiometabolic health in young, adult women.
研究年轻女性中客观测量的久坐行为、低强度体力活动与心血管代谢健康标志物之间的关联。
对 50 名年轻成年女性进行心血管疾病危险因素、胰岛素抵抗稳态模型评估（HOMA-IR）、脂质蓄积产物和炎症标志物的测量。使用加速度计在 7 天内评估久坐时间（<150 计数/分钟）、低强度体力活动（150-2,689 计数/分钟）和中等到剧烈体力活动（MVPA；≥2,690 计数/分钟）。多元回归分析了久坐行为和低强度体力活动与心血管代谢健康的独立关联。协变量包括 MVPA、心肺功能（VO2peak）和体重以及身体成分。
久坐行为与甘油三酯（p = 0.03）和脂质蓄积产物（p = 0.02）独立相关，与 MVPA 无关。这些关联在考虑 VO2peak 和体重或身体成分后减弱（p ≥ 0.05）。在调整所有协变量后，低强度体力活动与甘油三酯和脂质蓄积产物独立相关（p < 0.05）。低强度体力活动与 HOMA-IR 的关联与 MVPA 独立（p = 0.02），但在考虑 VO2peak 和体重或身体成分后减弱（p > 0.05）。
久坐行为和低强度体力活动与年轻成年女性的心血管代谢健康标志物独立相关。我们的数据表明，VO2peak 和身体成分可能是这些关联的重要中介。减少久坐行为和增加低强度体力活动可能对维持年轻成年女性的心血管代谢健康很重要。
