Almpani Konstantinia, Kantarci Alpdogan
Front Oral Biol. 2016;18:80-91. doi: 10.1159/000382048. Epub 2015 Nov 24.
While acceleration of the orthodontic tooth movement by surgical techniques has been shown to be effective for decades, noninvasive and nonsurgical methods have always been preferred by both the clinicians and the patients. These techniques have ranged from application of biological molecules to innovative technologies such as resonance vibration, cyclic forces, light electrical currents, magnetic field forces, low-intensity laser irradiation and low-level light therapy. Endogenously produced biologicals have been tested based on their roles in the turnover of alveolar bone in response to orthodontic tooth movement as well as during wound healing. The premise behind this approach is that these exogenously applied compounds will mimic their counterparts produced in vivo. Meanwhile, technologies tested so far target these pathways for the acceleration of the orthodontic tooth movement. All these approaches have shown favorable outcomes with varying success. This chapter presents the current knowledge and a discussion over their limitations with an emphasis on the mechanism of action for each technique.
几十年来，虽然手术技术加速正畸牙齿移动已被证明是有效的，但临床医生和患者一直更喜欢非侵入性和非手术方法。这些技术的范围从生物分子的应用到创新技术，如共振振动、循环力、弱电流、磁场力、低强度激光照射和低水平光疗法。内源性产生的生物制剂已根据它们在正畸牙齿移动以及伤口愈合过程中对牙槽骨周转的作用进行了测试。这种方法背后的前提是，这些外源性应用的化合物将模仿体内产生的对应物。同时，迄今为止测试的技术针对这些途径来加速正畸牙齿移动。所有这些方法都显示出了不同程度的良好效果。本章介绍了当前知识，并对其局限性进行了讨论，重点是每种技术的作用机制。
