Englhard Anna S, Wiedmann Maximilian, Ledderose Georg J, Lemieux Bryan, Badran Alan, Chen Zhongping, Betz Christian S, Wong Brian J
Department of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University Munich, Munich, Germany.
Department of Biomedical Engineering, University of California, Irvine, Irvine, California, U.S.A.
Laryngoscope. 2016 Mar;126(3):E97-E102. doi: 10.1002/lary.25785. Epub 2015 Nov 24.
OBJECTIVES/HYPOTHESIS: To evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals.
Prospective individual cohort study.
For 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible endoscope.
INV angle measured by OCT was found to be 18.3° ± 3.1° (mean ± standard deviation). The cross-sectional area was 0.65 ± 0.23 cm(2) . The INV angle measured by endoscopy was 18.8° ± 6.9°. There was no statistically significant difference between endoscopy and OCT concerning the mean INV angle (P = .778), but there was a significant difference in test precision (coefficient of variance 50% vs. 15%; P < .001).
LR-OCT proved to be a fast and easily performed method. OCT could accurately quantify the INV area. The values of the angle and the cross-sectional area of the INV were reproducible and correlated well with the data seen with other methods. Changes in size could be reliably delineated. Endoscopy showed similar values but was significantly less precise.
2b. Laryngoscope, 126:E97-E102, 2016.
目的/假设：首次评估对健康个体鼻内阀（INV）区域进行远距离傅里叶域光学相干断层扫描（LR - OCT）成像的可行性和方法。
前瞻性个体队列研究。
对16名个体的每个鼻孔进行OCT检查。测量INV的角度和横截面积。将OCT图像与用柔性内窥镜记录的相应数字图片进行比较。
通过OCT测量的INV角度为18.3°±3.1°（平均值±标准差）。横截面积为0.65±0.23 cm²。通过内窥镜检查测量的INV角度为18.8°±6.9°。在内窥镜检查和OCT之间，关于平均INV角度没有统计学上的显著差异（P = 0.778），但在测试精度上有显著差异（变异系数分别为50%和15%；P < 0.001）。
LR - OCT被证明是一种快速且易于实施的方法。OCT能够准确量化INV区域。INV的角度和横截面积值具有可重复性，并且与其他方法获得的数据相关性良好。大小变化能够可靠地描绘出来。内窥镜检查显示出相似的值，但精度明显较低。
2b。《喉镜》，2016年，第126卷，E97 - E102页
