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国家基本药物制度实施后药品价格的短期差异:以中国江西省农村地区为例

Short-term differences in drug prices after implementation of the national essential medicines system: A case study in rural Jiangxi Province, China.

作者信息

Wang Junyong, Liu Xia, Wang Suzhen, Chen Heli, Wang Xun, Zhou Wei, Wang Li, Zhu Yanchen, Zheng Xianping, Hao Mo

机构信息

Collaborative Innovation Center of Health Risks Governance, School of Public Health, Fudan University, Shanghai, China ; Department of Preventive Medicine, Health Development and Policy Research Center, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.

Department of Preventive Medicine, Health Development and Policy Research Center, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.

出版信息

Indian J Pharmacol. 2015 Sep-Oct;47(5):535-9. doi: 10.4103/0253-7613.165192.

Abstract

OBJECTIVES

China's 2009 national essential medicine system (NEMS) was designed to reduce prices through a zero-markup policy and a centralized bidding system. To analyze NEMS's short-term impact on drug prices, we estimated the retail and wholesale prices before and after the reform at health institutions in rural Jiangxi Province.

MATERIALS AND METHODS

We undertook two cross-sectional surveys of prices of 39 medicines in November 2008 and May 2010, calculated inflation adjusted prices, and used the Wilcoxon signed-rank and rank-sum tests to examine price changes at different health institutions.

RESULTS

Retail prices at pilot (P < 0.01) and nonpilot (P < 0.01) township health centers decreased significantly, whereas the declines at retail pharmacies (P = 0.57) and village clinics (P = 0.29) were insignificant. The decline at pilot township health centers was the largest, compared with other kinds of health institutions (P < 0.01). Retail prices of essential and non-essential medicines declined significantly at pilot facilities (P < 0.05); price drops for non-essential medicines occurred only at pilot facilities (P < 0.05). No significant decline of wholesale prices were found at pilot (P = 0.86) and nonpilot units (P = 0.18), retail pharmacies (P = 0.18), and village clinics (P = 0.20). The wholesale prices changes at pilot units before and after the reform were higher than at nonpilot public units (P < 0.05), retail pharmacies (P < 0.05), and village clinics (P < 0.05).

CONCLUSION

While the NEMS zero-markup policy significantly reduced retail prices at pilot health institutions, the centralized bidding system was insufficient to lower wholesale prices. A drug price management system should be constructed to control medicine prices and a long-term price information system is needed to monitor price changes.

摘要

目的

中国2009年国家基本药物制度(NEMS)旨在通过零差率政策和集中招标系统降低药品价格。为分析NEMS对药品价格的短期影响,我们估算了江西省农村医疗机构改革前后的零售价格和批发价格。

材料与方法

我们于2008年11月和2010年5月对39种药品价格进行了两次横断面调查,计算了经通胀调整后的价格,并使用Wilcoxon符号秩和检验及秩和检验来检验不同医疗机构的价格变化。

结果

试点乡镇卫生院(P < 0.01)和非试点乡镇卫生院(P < 0.01)的零售价格显著下降,而零售药店(P = 0.57)和村卫生室(P = 0.29)的价格下降不显著。与其他类型的医疗机构相比,试点乡镇卫生院的降幅最大(P < 0.01)。试点机构中基本药物和非基本药物的零售价格均显著下降(P < 0.05);非基本药物的价格下降仅发生在试点机构(P < 0.05)。试点单位(P = 0.86)和非试点单位(P = 0.18)、零售药店(P = 0.18)以及村卫生室(P = 0.20)的批发价格均未出现显著下降。改革前后试点单位的批发价格变化高于非试点公立单位(P < 0.05)、零售药店(P < 0.05)和村卫生室(P < 0.05)。

结论

虽然NEMS零差率政策显著降低了试点医疗机构的零售价格,但集中招标系统不足以降低批发价格。应构建药品价格管理系统以控制药品价格,并且需要一个长期价格信息系统来监测价格变化。

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