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中国领先的医药改革真的解决了医疗服务费用过高的问题吗?一项实证研究的证据。

Does the leading pharmaceutical reform in China really solve the issue of overly expensive healthcare services? Evidence from an empirical study.

作者信息

He Yunzhen, Dou Guanshen, Huang Qiaoyun, Zhang Xinyu, Ye Yingfeng, Qian Mengcen, Ying Xiaohua

机构信息

Department of Health Economics, School of Public Health, Fudan University, Shanghai, China.

出版信息

PLoS One. 2018 Jan 16;13(1):e0190320. doi: 10.1371/journal.pone.0190320. eCollection 2018.

Abstract

BACKGROUND

Healthcare system reform of Sanming city has become a leading healthcare reform model in China. It has developed a rigorous pharmaceutical reform consisted of the Zero Mark-up Drug Policy and the Centralized Procurement of Medicine Policy to bring down drug expenses and total health expenditures. However, despite the credit and much attention have been given to Sanming's pharmaceutical reform, its impact still remains unclear. Therefore, the purpose of this study was to explore the impact of the pharmaceutical reform of Sanming on both drug and total health expenditures.

METHODS

Interrupted time series analysis with three segments divided by two intervention points was employed to evaluate the impact of the pharmaceutical reform. Segment 1 was the pre-reform period which captured the baseline information. Segment 2 occurred after the first intervention point when the Zero Mark-up Drug Policy was implemented, whereas Segment 3 was after the implementation of the Centralized Procurement of Medicine Policy. Primary outcomes are outpatient drug expenditure, outpatient total health expenditure, inpatient drug expenditure, and inpatient total health expenditure. Data spanning from May 2012 to May 2014 are included.

RESULTS

Both drug and total health expenditures exhibited rising trends before any policy was carried out. The launch of Zero Mark-up Drug Policy led to significant instant reductions in levels of outpatient drug expenditure (coefficient = -6,602.99, p<0.01), outpatient total health expenditure (coefficient = -9,958.58, p<0.05), inpatient drug expenditure (coefficient = -7,520.90, p<0.01), and inpatient total health expenditure (coefficient = -16,737, p<0.01). Moreover, the previous upward trends were changed into downward trends for inpatient drug expenditure (coefficient = -2,747.02, p = 0.00) and total health expenditure (coefficient = -3,069.29, p = 0.12). However, after the implementation of Centralized Procurement of Medicine Policy, we observed no significant instant level changes and also, the inpatient drug expenditure (coefficient = 372.95, p = 0.01) and total health expenditure (coefficient = 788.76, p = 0.06) resumed upward trends again.

CONCLUSIONS

Although the pharmaceutical reform could control or reduced drug expenditure and total health expenditure in short term, expenditures gradually resumed growing again and reached or even exceeded their baseline levels of pre-reform period, indicating the effect became weakened or even faded out in long term. In all, the pharmaceutical reform as a whole failed to meet its goal of combating sharp growth of drug and total health expenditure.

摘要

背景

三明市的医疗体系改革已成为中国领先的医疗改革模式。它制定了一项严格的药品改革措施,包括药品零加成政策和药品集中采购政策,以降低药品费用和总体医疗支出。然而,尽管三明的药品改革备受赞誉和关注,但其影响仍不明确。因此,本研究的目的是探讨三明药品改革对药品和总体医疗支出的影响。

方法

采用以两个干预点划分的三个阶段的中断时间序列分析来评估药品改革的影响。阶段1是改革前时期,获取基线信息。阶段2发生在第一个干预点之后,即实施药品零加成政策时,而阶段3是在实施药品集中采购政策之后。主要结果是门诊药品支出、门诊总体医疗支出、住院药品支出和住院总体医疗支出。纳入了2012年5月至2014年5月的数据。

结果

在任何政策实施之前,药品和总体医疗支出均呈现上升趋势。药品零加成政策的实施导致门诊药品支出水平(系数=-6,602.99,p<0.01)、门诊总体医疗支出(系数=-9,958.58,p<0.05)、住院药品支出(系数=-7,520.90,p<0.01)和住院总体医疗支出(系数=-16,737,p<0.01)显著立即下降。此外,住院药品支出(系数=-2,747.02,p = 0.00)和总体医疗支出(系数=-3,069.29,p = 0.12)之前的上升趋势转变为下降趋势。然而,在实施药品集中采购政策之后,我们观察到没有显著的即时水平变化,并且住院药品支出(系数=372.95,p = 0.01)和总体医疗支出(系数=788.76,p = 0.06)再次恢复上升趋势。

结论

尽管药品改革在短期内可以控制或降低药品支出和总体医疗支出,但支出逐渐再次恢复增长,并达到甚至超过改革前时期的基线水平,表明从长期来看效果减弱甚至消失。总体而言,药品改革作为一个整体未能实现其遏制药品和总体医疗支出急剧增长的目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f2e/5770029/2ba6d83753e2/pone.0190320.g001.jpg

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