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血管疾病时红细胞的结构、氧运输功能及离子组成研究

Study of the Structure, Oxygen-Transporting Functions, and Ionic Composition of Erythrocytes at Vascular Diseases.

作者信息

Revin Viktor V, Gromova Natalia V, Revina Elvira S, Mel'nikova Natalya A, Balykova Larisa A, Solomadin Ilia N, Tychkov Alexander Yu, Revina Nadezhda V, Gromova Oksana Yu, Anashkina Irina V, Yakushkin Viktor A

机构信息

FGBOUVPO "N.P. Ogarev Mordovia State University", Saransk 430005, Russia.

GBUZ RM "National Hospital for War Veterans", Saransk 430005, Russia.

出版信息

Biomed Res Int. 2015;2015:973973. doi: 10.1155/2015/973973. Epub 2015 Oct 27.

Abstract

The present paper explores the role of erythrocytes in the pathogenesis of vascular diseases. The state of erythrocytes, their ionic composition and structure, and properties of erythrocytes hemoglobin were studied by using laser interference microscopy, Raman scattering spectroscopy, and capillary electrophoresis. In patients suffering from vascular disorders we identified statistically significant changes in the shape of erythrocytes, their ionic composition, and redistribution of hemoglobin throughout cells.

摘要

本文探讨红细胞在血管疾病发病机制中的作用。通过激光干涉显微镜、拉曼散射光谱和毛细管电泳研究了红细胞的状态、离子组成和结构以及红细胞血红蛋白的特性。在患有血管疾病的患者中,我们发现红细胞形状、离子组成以及血红蛋白在整个细胞中的重新分布存在统计学上的显著变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5647/4639635/a3b3aadab893/BMRI2015-973973.001.jpg

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