• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口服处方药的意外摄入:一项多中心调查。

Accidental ingestions of oral prescription drugs: a multicenter survey.

作者信息

Jacobson B J, Rock A R, Cohn M S, Litovitz T

机构信息

US Consumer Product Safety Commission, Directorate for Health Sciences, Washington, DC 20207.

出版信息

Am J Public Health. 1989 Jul;79(7):853-6. doi: 10.2105/ajph.79.7.853.

DOI:10.2105/ajph.79.7.853
PMID:2660604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1349665/
Abstract

Accidental ingestion of oral prescription drugs by children under age five continues to be a public health problem. A telephone survey of 1,866 ingestion incidents reported to nine poison control centers was conducted in the spring of 1986. Accidental ingestion occurred most often with a two-year-old child (42 per cent) in their own home (82 per cent). Thirty-five per cent of the toxic drugs ingested at home belonged to someone other than the immediate family, most often a grandparent. Toxic drugs were more often out of their usual storage location and in non-child-resistant prescription packaging, a nonprescription container, or in no container. Twenty-two per cent of all child-resistant packages were non-functional. Overall, at least 61 per cent of all medications had no child-resistant barrier at the time of ingestion. Accessible storage locations such as the kitchen counter, table top, or top of a dresser or bedside table greatly increased the risk of accidental ingestion. These results suggest the need for effective child-resistant packaging that is easier for all adults to use.

摘要

五岁以下儿童意外摄入口服处方药仍是一个公共卫生问题。1986年春季,对向九个中毒控制中心报告的1866起摄入事件进行了电话调查。意外摄入最常发生在两岁儿童身上(42%),且发生在他们自己家中(82%)。在家中摄入的有毒药物中,35%属于直系亲属以外的人,最常见的是祖父母。有毒药物更常放在其通常的储存位置之外,且装在非儿童安全的处方包装、非处方容器或无容器中。所有儿童安全包装中,22%无法正常使用。总体而言,所有药物中至少61%在摄入时没有儿童安全防护。厨房柜台、桌面、梳妆台顶部或床头柜顶部等易于拿到的储存位置大大增加了意外摄入的风险。这些结果表明需要有效的儿童安全包装,且所有成年人都更容易使用。

相似文献

1
Accidental ingestions of oral prescription drugs: a multicenter survey.口服处方药的意外摄入:一项多中心调查。
Am J Public Health. 1989 Jul;79(7):853-6. doi: 10.2105/ajph.79.7.853.
2
An evaluation of the Poison Prevention Packaging Act.《预防中毒包装法案》评估
Pediatrics. 1982 Mar;69(3):363-70.
3
Accidental poisoning in childhood: a multicentre survey. 2. The role of packaging in accidents involving medications.儿童意外中毒:一项多中心调查。2. 包装在涉及药物的事故中的作用。
Hum Toxicol. 1987 Jul;6(4):303-14. doi: 10.1177/096032718700600407.
4
The safety effects of child-resistant packaging for oral prescription drugs. Two decades of experience.儿童安全型口服处方药包装的安全效果。二十年的经验。
JAMA. 1996 Jun 5;275(21):1661-5.
5
Child-resistant packaging for certain over-the-counter drug products. Final rule.某些非处方药品的儿童安全包装。最终规则。
Fed Regist. 2001 Aug 2;66(149):40111-6.
6
Ingestion of Over-the-Counter Liquid Medications: Emergency Department Visits by Children Aged Less Than 6 Years, 2012-2015.2012-2015 年,6 岁以下儿童因摄入非处方液体药物到急诊科就诊的情况。
Am J Prev Med. 2019 Feb;56(2):288-292. doi: 10.1016/j.amepre.2018.10.004. Epub 2018 Dec 17.
7
Effect of cough and cold medication restriction and label changes on pediatric ingestions reported to United States poison centers.咳嗽和感冒药物限制及标签变化对美国中毒控制中心报告的儿科药物摄入的影响。
J Pediatr. 2013 Nov;163(5):1372-6. doi: 10.1016/j.jpeds.2013.04.054. Epub 2013 Jun 12.
8
Accidental pediatric ingestion, hospital charges and failure to utilize a poison control center.儿童意外摄入、医院收费及未利用中毒控制中心的情况。
WMJ. 1999 Nov;98(7):29-33.
9
Ingestion of prescription drugs by children: an epidemiologic study.儿童服用处方药:一项流行病学研究。
South Med J. 1989 Dec;82(12):1468-71, 1478. doi: 10.1097/00007611-198912000-00004.
10
Unintentional child poisonings treated in United States hospital emergency departments: national estimates of incident cases, population-based poisoning rates, and product involvement.美国医院急诊科治疗的儿童意外中毒情况:事件病例的全国估计数、基于人群的中毒率及相关产品情况。
Pediatrics. 2008 Dec;122(6):1244-51. doi: 10.1542/peds.2007-3551.

引用本文的文献

1
Unsafe storage of household medicines: results from a cross-sectional study of four-year-olds from the 2004 Pelotas birth cohort (Brazil).家庭药品的不安全储存:来自2004年佩洛塔斯出生队列(巴西)四岁儿童横断面研究的结果
BMC Pediatr. 2019 Jul 12;19(1):235. doi: 10.1186/s12887-019-1597-1.
2
Child-resistant and tamper-resistant packaging: A systematic review to inform tobacco packaging regulation.防儿童开启和防篡改包装:为烟草包装监管提供信息的系统评价。
Prev Med. 2017 Feb;95:89-95. doi: 10.1016/j.ypmed.2016.11.013. Epub 2016 Dec 9.
3
Emergency hospitalizations for unsupervised prescription medication ingestions by young children.幼儿因无监管的处方药摄入导致的急诊住院情况。
Pediatrics. 2014 Oct;134(4):e1009-16. doi: 10.1542/peds.2014-0840. Epub 2014 Sep 15.
4
Efficacy of flow restrictors in limiting access of liquid medications by young children.流量限制器在限制幼儿使用液体药物方面的效果。
J Pediatr. 2013 Oct;163(4):1134-9.e1. doi: 10.1016/j.jpeds.2013.05.045. Epub 2013 Jul 26.
5
In-home Drug Storage and Self-medication with Antimicrobial Drugs in Basrah, Iraq.伊拉克巴士拉的家庭药品储存与抗菌药物自我药疗
Oman Med J. 2010 Apr;25(2):79-87. doi: 10.5001/omj.2010.25.
6
The last mile: taking the final steps in preventing pediatric pharmaceutical poisonings.最后一英里:在预防儿童药物中毒方面迈出最后几步。
J Pediatr. 2012 Feb;160(2):190-2. doi: 10.1016/j.jpeds.2011.09.020. Epub 2011 Nov 5.
7
Epidemiology of drug overdose in children.儿童药物过量的流行病学
Drug Saf. 1993 Oct;9(4):291-308. doi: 10.2165/00002018-199309040-00007.
8
Poisoning in children.儿童中毒
Pharm World Sci. 1993 Oct 15;15(5):193-6. doi: 10.1007/BF01880625.
9
Household survey of child-safe packaging for medications.药品儿童安全包装的家庭调查。
Public Health Rep. 1990 Jul-Aug;105(4):430-2.

本文引用的文献

1
Accidental poisoning in childhood from the epidemiological viewpoint-An analysis of 323 cases of poisoning in children under eight years of age-.从流行病学角度看儿童意外中毒——对323例8岁以下儿童中毒病例的分析——
Vet Hum Toxicol. 1981 Oct;23(5):321-7.
2
Accidental poisoning in young children.幼儿意外中毒。
J Epidemiol Community Health. 1982 Mar;36(1):31-4. doi: 10.1136/jech.36.1.31.
3
An evaluation of the Poison Prevention Packaging Act.《预防中毒包装法案》评估
Pediatrics. 1982 Mar;69(3):363-70.
4
Epidemiology of accidental poisoning in children.儿童意外中毒的流行病学
Med J Aust. 1983 Aug 20;2(4):181-3. doi: 10.5694/j.1326-5377.1983.tb122400.x.
5
Circumstances surrounding deaths from accidental poisoning 1974-80.1974年至1980年意外中毒死亡的相关情况。
Arch Dis Child. 1983 Jul;58(7):544-6. doi: 10.1136/adc.58.7.544.
6
Poisoning in childhood.儿童中毒
Practitioner. 1983 Sep;227(1383):1451-7.
7
Acute poisonings of children in Oslo. A one year prospective study.奥斯陆儿童急性中毒情况。一项为期一年的前瞻性研究。
Acta Paediatr Scand. 1983 Jul;72(4):553-7. doi: 10.1111/j.1651-2227.1983.tb09770.x.
8
The environment away from home as a source of potential poisoning.离家环境是潜在中毒的一个来源。
Am J Dis Child. 1984 Nov;138(11):1014-7. doi: 10.1001/archpedi.1984.02140490014003.
9
Accidental poisoning in childhood: five year urban population study with 15 year analysis of fatality.儿童期意外中毒:为期五年的城市人口研究及15年死亡情况分析
Br Med J (Clin Res Ed). 1984 Jan 7;288(6410):44-6. doi: 10.1136/bmj.288.6410.44.
10
Accident epidemiology and the design of the residential environment.事故流行病学与居住环境设计
Hum Factors. 1972 Oct;14(5):405-20. doi: 10.1177/001872087201400504.