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土耳其某大学医院重症创伤性脑损伤预后因素的回顾性分析

Retrospective Analysis of Prognostic Factors of Severe Traumatic Brain Injury in a University Hospital in Turkey.

作者信息

Ozyurt Erhan, Goksu Ethem, Cengiz Melike, Yilmaz Murat, Ramazanoglu Atilla

机构信息

Akdeniz University, School of Medicine, Department of Anaesthesiology and Reanimation, Antalya, Turkey.

出版信息

Turk Neurosurg. 2015;25(6):877-82. doi: 10.5137/1019-5149.JTN.9181-13.0.

DOI:10.5137/1019-5149.JTN.9181-13.0
PMID:26617136
Abstract

AIM

To examine the use of prognostic factors such as age, Glasgow Coma Scale (GCS) score, pupil reactivity and computerized tomography (CT) findings for predicting the prognosis of severe traumatic brain injury (TBI) patients in Turkey.

MATERIAL AND METHODS

We retrospectively evaluated TBI patients who were accepted to Akdeniz University Intensive Care Unit between 1 January 2007 and 31 December 2009. Patient data were collected from the hospital information system. Marshall CT classification was performed and CT findings were noted. The Glasgow outcome scale (GOS) score of patients was calculated according to their 6-months follow up.

RESULTS

A total of 101 patients with severe TBI were studied. The mean age of the patients was 34.7 ± 14.1 years. Of these, male patients (81.2%) were dominant and road accidents (83.2%) were the most common mechanism of TBI development. In addition, poor neurological outcome was detected in 58.4% of the patients and 29 patients (28.7%) died. The mechanism of injury (p = 0.34), gender (p = 0.64) or age (p = 0.34) did not lead to a difference in neurologic outcomes while the GCS score (p = 0.01), pupillary reactivity (p = 0.000), Marshall CT classification (p = 0.01) and the presence of traumatic subarachnoid haemorrhage (p = 0.04) affected the GOS scores.

CONCLUSION

In our study, GCS score, CT findings and pupil reactivity were prominent as prognostic factors, but a relationship between age and prognosis was not observed.

摘要

目的

研究年龄、格拉斯哥昏迷量表(GCS)评分、瞳孔反应性和计算机断层扫描(CT)结果等预后因素在预测土耳其重型创伤性脑损伤(TBI)患者预后中的应用。

材料与方法

我们回顾性评估了2007年1月1日至2009年12月31日期间入住阿克德尼兹大学重症监护病房的TBI患者。患者数据从医院信息系统收集。进行了马歇尔CT分类并记录CT结果。根据患者6个月的随访情况计算格拉斯哥预后量表(GOS)评分。

结果

共研究了101例重型TBI患者。患者的平均年龄为34.7±14.1岁。其中,男性患者占主导(81.2%),道路交通事故(83.2%)是TBI发生最常见的机制。此外,58.4%的患者神经功能预后不良,29例患者(28.7%)死亡。损伤机制(p = 0.34)、性别(p = 0.64)或年龄(p = 0.34)在神经功能预后方面无差异,而GCS评分(p = 0.01)、瞳孔反应性(p = 0.000)、马歇尔CT分类(p = 0.01)和创伤性蛛网膜下腔出血的存在(p = 0.04)影响GOS评分。

结论

在我们的研究中,GCS评分、CT结果和瞳孔反应性是突出的预后因素,但未观察到年龄与预后之间的关系。

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