van Rappard Dominique C, Mekkes Jan R, Tzellos Thrasivoulos
Department of Dermatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Department of Dermatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.
Dermatol Clin. 2016 Jan;34(1):69-80. doi: 10.1016/j.det.2015.08.012.
Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease. Several treatment modalities are available, but most of them lack high-quality evidence. A systematic search was performed to identify all randomized controlled trials for the treatment of HS in order to review and evaluate the evidence. Recommendations for future randomized controlled trials include using validated scores, inclusion of patient rated outcomes, and thorough report of side effects. Evidence for long-term treatment and benefit/risk ratio of available treatment modalities is needed in order to enhance evidence-based treatment in daily clinical practice. Combining surgery with antiinflammatory treatment warrants further investigation.
化脓性汗腺炎（HS）是一种慢性、炎症性、复发性、使人衰弱的皮肤病。有多种治疗方式可供选择，但其中大多数缺乏高质量证据。为了回顾和评估证据，我们进行了一项系统检索，以确定所有治疗HS的随机对照试验。对未来随机对照试验的建议包括使用经过验证的评分、纳入患者自评结果以及全面报告副作用。为了在日常临床实践中加强循证治疗，需要有关长期治疗以及现有治疗方式的获益/风险比的证据。将手术与抗炎治疗相结合值得进一步研究。
