Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Department of Dermatology, University of Wisconsin Hospital and Clinics, Madison, Wisconsin.
J Am Acad Dermatol. 2020 Aug;83(2):554-562. doi: 10.1016/j.jaad.2020.04.009. Epub 2020 Apr 11.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting intertriginous skin areas, and it is characterized by recurrent painful episodes of inflammatory drainage. Although the pathophysiology of HS is not fully understood, recent research points to an imbalance of cytokines as a contributing factor to the associated symptoms of purulent drainage and sinus tract formation. HS lesions are often characterized by a superimposed pathogenic/commensal bacterial infection that can improve with targeted antibiotic therapy. New medical treatments have emerged in recent years, many of which specifically work against a variety of proinflammatory mediators associated with HS. These newer, specified treatment options, in conjunction with surgery and lasers, are thought to provide positive outcomes and an overall improvement in quality of life in patients with HS.
化脓性汗腺炎（HS）是一种影响间擦部位皮肤的慢性炎症性疾病，其特征是反复发作的炎症性引流疼痛。虽然 HS 的病理生理学尚未完全了解，但最近的研究指出细胞因子失衡是与脓性引流和窦道形成相关症状的一个促成因素。HS 病变常伴有继发的致病性/共生细菌感染，针对性抗生素治疗可改善这种感染。近年来出现了许多新的医疗治疗方法，其中许多专门针对与 HS 相关的各种促炎介质。这些较新的、特定的治疗选择，结合手术和激光，被认为可以为 HS 患者提供积极的结果和整体生活质量的改善。
