• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

异维A酸治疗后出现严重面部多毛症:一种报道不足的情况。

Severe Facial Hirsutism Following Isotretinoin Therapy: An Under-reported Entity.

作者信息

Ramot Yuval, Sheffer Sivan, Zlotogorski Abraham

机构信息

Department of Dermatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

出版信息

Int J Trichology. 2015 Jul-Sep;7(3):129-30. doi: 10.4103/0974-7753.167466.

DOI:10.4103/0974-7753.167466
PMID:26622158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4639958/
Abstract

Hirsutism is usually a manifestation of hyperandrogenism, and iatrogenic causes for excess hair growth are uncommon. Here, we report on a 48-year-old female patient, who developed severe excess facial hair following treatment with isotretinoin for papulopustular rosacea. To the best of our knowledge, only one case has been reported before, and not in the dermatology literature. Taking into consideration the fact that isotretinoin is a widely prescribed medication in the dermatology practice, information on its possible adverse effects is of major importance for the treating dermatologist.

摘要

多毛症通常是雄激素过多的一种表现,医源性导致毛发过度生长的情况并不常见。在此,我们报告一名48岁女性患者,她在使用异维A酸治疗丘疹脓疱型玫瑰痤疮后出现严重的面部毛发过度生长。据我们所知,此前仅报告过1例,且未见于皮肤科文献。考虑到异维A酸是皮肤科临床中广泛使用的药物,了解其可能的不良反应信息对皮肤科治疗医生至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aca8/4639958/0f4aec089f83/IJT-7-129-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aca8/4639958/ef2d995a29c7/IJT-7-129-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aca8/4639958/0f4aec089f83/IJT-7-129-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aca8/4639958/ef2d995a29c7/IJT-7-129-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aca8/4639958/0f4aec089f83/IJT-7-129-g002.jpg

相似文献

1
Severe Facial Hirsutism Following Isotretinoin Therapy: An Under-reported Entity.异维A酸治疗后出现严重面部多毛症:一种报道不足的情况。
Int J Trichology. 2015 Jul-Sep;7(3):129-30. doi: 10.4103/0974-7753.167466.
2
A Randomized-Controlled Trial of Oral Low-Dose Isotretinoin for Difficult-To-Treat Papulopustular Rosacea.口服低剂量异维A酸治疗难治性丘疹脓疱型酒渣鼻的随机对照试验
J Invest Dermatol. 2016 Jun;136(6):1124-1129. doi: 10.1016/j.jid.2016.01.025. Epub 2016 Feb 7.
3
Very low-dose isotretinoin in mild to moderate papulopustular rosacea; a retrospective review of 52 patients.极低剂量异维A酸治疗轻至中度丘疹脓疱型玫瑰痤疮:52例患者的回顾性研究
Australas J Dermatol. 2018 Feb;59(1):26-30. doi: 10.1111/ajd.12522. Epub 2016 Jul 20.
4
Comparison of combined azelaic acid cream plus oral minocycline with oral isotretinoin in severe acne.壬二酸乳膏联合口服米诺环素与口服异维A酸治疗重度痤疮的比较
Eur J Dermatol. 2001 Nov-Dec;11(6):538-44.
5
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne.螺内酯对比安慰剂或与类固醇联合用于治疗多毛症和/或痤疮。
Cochrane Database Syst Rev. 2003(4):CD000194. doi: 10.1002/14651858.CD000194.
6
Dermatological indications for the use of isotretinoin beyond acne.异维A酸在痤疮以外的皮肤科适应症。
J Dermatolog Treat. 2018 Nov;29(7):698-705. doi: 10.1080/09546634.2018.1445194. Epub 2018 Mar 14.
7
Isotretinoin (roaccutane) usage--a South African consensus guideline. National Dermatology Working Group.异维A酸(罗可坦)的使用——南非共识指南。国家皮肤病学工作组。
S Afr Med J. 1997 Oct;87(10 Pt 2):1410-3.
8
Roaccutane treatment guidelines: results of an international survey.异维A酸治疗指南:一项国际调查结果
Dermatology. 1997;194(4):351-7. doi: 10.1159/000246134.
9
Androgen excess: Investigations and management.雄激素过多:检查与管理。
Best Pract Res Clin Obstet Gynaecol. 2016 Nov;37:98-118. doi: 10.1016/j.bpobgyn.2016.05.003. Epub 2016 May 19.
10
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne.螺内酯对比安慰剂或联合类固醇治疗多毛症和/或痤疮。
Cochrane Database Syst Rev. 2001(4):CD000194. doi: 10.1002/14651858.CD000194.

本文引用的文献

1
Adverse effects of acne medications: recognition and management.痤疮药物的不良反应:识别与管理。
Am J Clin Dermatol. 2015 Aug;16(4):231-242. doi: 10.1007/s40257-015-0127-7.
2
Hirsutism: an evidence-based treatment update.多毛症:基于证据的治疗更新。
Am J Clin Dermatol. 2014 Jul;15(3):247-66. doi: 10.1007/s40257-014-0078-4.
3
Insulin sensitivity, androgens and isotretinoin therapy in women with severe acne.女性严重痤疮患者的胰岛素敏感性、雄激素与异维 A 酸治疗。
J Dermatolog Treat. 2014 Apr;25(2):119-22. doi: 10.3109/09546634.2012.751482. Epub 2013 Feb 3.
4
Hirsutism in women.女性多毛症。
Am Fam Physician. 2012 Feb 15;85(4):373-80.
5
Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.多毛症的流行病学、诊断和管理:雄激素过多和多囊卵巢综合征学会的共识声明。
Hum Reprod Update. 2012 Mar-Apr;18(2):146-70. doi: 10.1093/humupd/dmr042. Epub 2011 Nov 6.
6
Evaluation and treatment of hirsutism in premenopausal women: an endocrine society clinical practice guideline.绝经前女性多毛症的评估与治疗:内分泌学会临床实践指南
J Clin Endocrinol Metab. 2008 Apr;93(4):1105-20. doi: 10.1210/jc.2007-2437. Epub 2008 Feb 5.
7
13-cis-Retinoic acid (isotretinoin) unmasking of clinical polycystic ovary syndrome.13-顺式维甲酸(异维甲酸)揭示临床多囊卵巢综合征。
Endocr Pract. 2007 Nov-Dec;13(7):776-9. doi: 10.4158/EP.13.7.776.
8
Androgen excess in women: experience with over 1000 consecutive patients.女性雄激素过多:对1000余例连续患者的经验总结。
J Clin Endocrinol Metab. 2004 Feb;89(2):453-62. doi: 10.1210/jc.2003-031122.
9
The evaluation and management of hirsutism.多毛症的评估与管理
Obstet Gynecol. 2003 May;101(5 Pt 1):995-1007. doi: 10.1016/s0029-7844(02)02725-4.
10
Hypertrichosis in females applying minoxidil topical solution and in normal controls.应用米诺地尔外用溶液的女性及正常对照者的多毛症
J Eur Acad Dermatol Venereol. 2003 May;17(3):271-5. doi: 10.1046/j.1468-3083.2003.00621.x.