Gamoh Shoko, Akiyama Hironori, Tominaga Kazuya, Nakajima Masahiro, Kakudo Kenji, Tanaka Akio, Shimizutani Kimishige
Department of Oral Radiology, Osaka Dental University, Osaka 540-0008, Japan.
Department of Oral Pathology, Osaka Dental University, Osaka 540-0008, Japan.
Oncol Lett. 2015 Aug;10(2):785-789. doi: 10.3892/ol.2015.3323. Epub 2015 Jun 4.
Keratocystic odontogenic tumors (KCOTs) and ameloblastomas are benign odontogenic tumors that primarily occur in the molar region of the mandible. However, it is uncommon for these tumors to arise simultaneously in a patient's jaw. The present study reported the diagnostic process and features of a rare case of the simultaneous occurrence of KCOT and ameloblastoma in the mandible of a 45-year-old male. Image-based diagnosis was challenging due to several conditions, including the intactness of the teeth and bone cortex as well as the sizes and locations of the lesions. Based on radiographic evidence, the patient was initially misdiagnosed and underwent a biopsy for a radicular cyst and a simple bone cyst prior to the correct diagnoses of KCOT and ameloblastoma, respectively. In addition, the present study discussed the diagnostic process of the present case and reviewed previous literature regarding the simultaneous occurrence of benign tumors of the jaw.
牙源性角化囊性瘤(KCOTs)和成釉细胞瘤是主要发生在下颌磨牙区的良性牙源性肿瘤。然而,这些肿瘤在患者颌骨中同时出现的情况并不常见。本研究报告了一例45岁男性下颌骨同时发生KCOT和成釉细胞瘤的罕见病例的诊断过程及特征。由于多种情况,包括牙齿和骨皮质的完整性以及病变的大小和位置,基于图像的诊断具有挑战性。根据影像学证据,患者最初被误诊,分别在正确诊断为KCOT和成釉细胞瘤之前,接受了针对根尖囊肿和单纯骨囊肿的活检。此外,本研究讨论了该病例的诊断过程,并回顾了以往关于颌骨良性肿瘤同时发生的文献。