Firth Norman, Alsarraf Abdulhameed, Vujcich Nathan, Kujan Omar
School of Dentistry, University of Queensland, Herston QLD, Australia.
Oral Medicine clinics, Ministry of Health, Kuwait.
Clin Pract. 2020 Jun 22;10(2):1205. doi: 10.4081/cp.2020.1205. eCollection 2020 May 19.
Odontogenic keratocyst (OKC) and ameloblastomas are distinct histopathologically diagnosed odontogenic lesions of the oral cavity. Both are primarily located in the posterior regions of the mandible, however, they can involve the maxilla as well. The occurrence of both an OKC and ameloblastoma in a patient is very uncommon. This case demonstrated such a lesion in the mandible of a 57 years old female. The diagnostic work-up and features of both lesions are illustrated with special focus on histopathological variances distinguishing OKC from ameloblastoma with the support of immunohistochemistry. This case highlights the importance of identifying accurate diagnoses for such lesions which may prompt clinical implications. Clinico-pathologic understanding of both lesions signifies the need for careful management plan and prevention of recurrence. Previously reported simultaneous occurrences of odontogenic cysts and/or tumors in the oral cavity are also reviewed.
牙源性角化囊肿（OKC）和成釉细胞瘤是口腔中经组织病理学诊断的不同牙源性病变。两者主要位于下颌骨后部，但也可累及上颌骨。患者同时发生OKC和成釉细胞瘤非常罕见。本病例展示了一名57岁女性下颌骨中的此类病变。通过免疫组织化学的支持，特别关注区分OKC与成釉细胞瘤的组织病理学差异，阐述了这两种病变的诊断检查和特征。该病例强调了对此类病变进行准确诊断的重要性，这可能会产生临床影响。对这两种病变的临床病理理解表明需要制定仔细的管理计划并预防复发。还回顾了先前报道的口腔中同时发生牙源性囊肿和/或肿瘤的情况。
