Dulskas Audrius, Bagurskas Paulius, Sinkevicius Zalvyras, Samalavicius Narimantas E
Department of Abdominal and General Surgery, National Cancer Institute, Vilnius University, Vilnius LT-08406, Lithuania.
Department of Abdominal and General Surgery, National Cancer Institute, Vilnius University, Vilnius LT-08406, Lithuania ; Centre of Oncosurgery, National Cancer Institute, Clinic of Internal Diseases, Family Medicine and Oncology, Faculty of Medicine, Vilnius University, Vilnius LT-08406, Lithuania.
Oncol Lett. 2015 Aug;10(2):1191-1193. doi: 10.3892/ol.2015.3290. Epub 2015 May 28.
Distant metastases from colorectal cancer (CRC) most frequently spread to the liver and lungs. CRC metastasis to the kidney is extremely rare and may be generally associated with an unfavorable prognosis. Thus, patients with metastatic CRC and kidney metastasis are a diagnostic and therapeutic challenge. The present study reported the case of a 42-year-old male with a local recurrence of CRC following sigmoid resection with partial mesorectal excision, which had infiltrated the urinary bladder, requiring partial resection of the urinary bladder wall. After 4 years, the patient developed a recurrent tumor localized in the upper pole of the left kidney and underwent left nephrectomy. The patient remained disease-free 6 months after the surgery.
结直肠癌(CRC)的远处转移最常扩散至肝脏和肺部。CRC转移至肾脏极为罕见,通常可能与预后不良相关。因此,患有转移性CRC且发生肾脏转移的患者在诊断和治疗方面颇具挑战。本研究报告了一例42岁男性患者的病例,该患者在乙状结肠切除并部分直肠系膜切除术后出现CRC局部复发,肿瘤已浸润膀胱,需行膀胱壁部分切除术。4年后,患者左肾上极出现复发性肿瘤,并接受了左肾切除术。术后6个月患者无疾病复发。