Mythili Sabesan, Malathi Narasimhan
Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Chennai, Tamil Nadu 600116, India.
Biomed Rep. 2015 Nov;3(6):743-748. doi: 10.3892/br.2015.500. Epub 2015 Jul 29.
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. The highest risk of fatality occurs within the initial hours of onset of AMI. Thus, early diagnosis of cardiac ischemia is critical for the effective management of patients with AMI. Improper diagnosis of patients with chest pain often leads to inappropriate admission of patients without AMI and vice versa. In addition to clinical history, physical examination, accurate electrocardiogram findings and assessment of cardiac biomarkers have an important role in the early diagnosis of acute ischemia. The present review discusses in detail the various cardiac biomarkers released during the event of an AMI.
急性心肌梗死(AMI)是全球发病和死亡的主要原因。AMI发病最初数小时内死亡风险最高。因此,心脏缺血的早期诊断对于AMI患者的有效管理至关重要。胸痛患者的误诊常常导致非AMI患者的不适当入院,反之亦然。除了临床病史、体格检查外,准确的心电图表现和心脏生物标志物评估在急性缺血的早期诊断中具有重要作用。本综述详细讨论了AMI发生过程中释放的各种心脏生物标志物。