[Effect of the glucose concentration in the maternal blood on the level of specific beta 1-glycoprotein].

The authors carried out studies on 20 women with normal pregnancy between 38 and 40 weeks gestation. Hypoglycemia, induced by insulin, was provoked in 10 of them, but hyperglycemia--in the other 10 women. Maternal blood samples for glucose and SP1 were taken on 15,30 and 60 min as well as on 2, 6, 12, 24 and 48 h after the onset of the trial. It was established that hypoglycemia, induced by insulin, the mean values of SP1 in the maternal serum on 24th hour were considerably higher, but in the induced hyperglycemia the values of SP1 were higher on the 24th h than on 60 respectively 120 min after the beginning of glucose infusion. The authors found that between serum concentration of SP1 and carbohydrate metabolism of the mother existed interrelationship.