Yin Rong-Hua, Bai Xue, Feng Tao, Dong Ze-Jun, Li Zheng-Hui, Liu Ji-Kai
a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
b University of Chinese Academy of Sciences , Beijing 100049 , China.
J Asian Nat Prod Res. 2016;18(4):354-9. doi: 10.1080/10286020.2015.1099525. Epub 2015 Dec 2.
One new lignan, fructusol A (1), and one new thiazine derivative, 2-hydroxy-xanthiazone (2), along with eight known ones, were isolated from the seeds of Xanthium strumarium. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods. Meanwhile, compounds 1-3 were tested for their antifungal activities against Candida albicans (ATCC 10231) in vitro. No one showed obvious inhibitions (MIC90 > 128 μg/ml).
从苍耳种子中分离出一种新的木脂素，苍耳醇A（1）和一种新的噻嗪衍生物，2-羟基氧杂蒽酮（2），以及八种已知化合物。通过广泛的光谱方法阐明了新化合物的结构。同时，对化合物1-3进行了体外抗白色念珠菌（ATCC 10231）的抗真菌活性测试。没有一个显示出明显的抑制作用（MIC90>128μg/ml）。
