Nau Cherie B, Schornack Muriel M, McLaren Jay W, Sit Arthur J
Department of Ophthalmology, Mayo Clinic, Rochester, MN.
Eye Contact Lens. 2016 Nov;42(6):350-353. doi: 10.1097/ICL.0000000000000214.
Compression of episcleral veins or deformation of tissue in the Schlemm's canal beneath the landing zone of scleral lenses could elevate intraocular pressure (IOP). We examined the effect of 2 hr of small-diameter scleral lens wear on IOP.
Twenty-nine participants, 29 ± 6 years old (mean ± SD) who experienced no history of eye disease or scleral lens wear, were included in the study. Each participant was fitted with a 15-mm Jupiter scleral lens on one eye (study eye). Intraocular pressure was measured in both eyes by pneumatonometry centrally on the cornea and peripherally on the sclera. The lens was then placed on one eye and was worn for 2 hr. Intraocular pressure was remeasured immediately after lens placement, at 1 and 2 hr of lens wear, and immediately after lens removal. Intraocular pressure after removal of the scleral lens was compared with IOP before placing the lens and to IOP in the control eye using paired t tests.
Immediately after removing the scleral lens, mean central IOP in the study eye (13.9 ± 3.1 mm Hg) was not different from mean central IOP in the control eye (13.5 ± 2.2 mm Hg, P = 0.4) or in the same eye before lens wear (13.6 ± 1.9 mm Hg, P = 0.6). There were also no differences in IOP measured peripherally at 2 hr of lens wear (P = 0.8).
Neophyte scleral lens wear of a 15-mm scleral lens for 2 hr does not increase IOP in healthy eyes.
巩膜静脉受压或巩膜镜着陆区下方施莱姆管内组织变形可升高眼压（IOP）。我们研究了佩戴小直径巩膜镜2小时对眼压的影响。
本研究纳入29名参与者，年龄29±6岁（均值±标准差），无眼部疾病或佩戴巩膜镜史。每位参与者一只眼睛（研究眼）佩戴15毫米的朱庇特巩膜镜。通过气动眼压计在角膜中央和巩膜周边测量双眼眼压。然后将镜片置于一只眼睛上佩戴2小时。在镜片放置后立即、佩戴镜片1小时和2小时时以及镜片摘除后立即重新测量眼压。使用配对t检验比较摘除巩膜镜后的眼压与放置镜片前的眼压以及对照眼的眼压。
摘除巩膜镜后立即测量，研究眼的平均中央眼压（13.9±3.1毫米汞柱）与对照眼的平均中央眼压（13.5±2.2毫米汞柱，P = 0.4）或同一只眼睛佩戴镜片前的眼压（13.6±1.9毫米汞柱，P = 0.6）无差异。佩戴镜片2小时时周边测量的眼压也无差异（P = 0.8）。
健康眼睛初次佩戴15毫米巩膜镜2小时不会升高眼压。
