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健康受试者和佩戴治疗性软性隐形眼镜患者的 Icare 眼压计和 Airpuff 眼压计的眼压比较测量。

Comparative measurement of intraocular pressure by Icare tonometry and Airpuff tonometry in healthy subjects and patients wearing therapeutic soft contact lenses.

机构信息

University Eye Hospital Freiburg, Killianstraße 5, 79106, Freiburg, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2013 Jul;251(7):1791-5. doi: 10.1007/s00417-013-2329-0. Epub 2013 Mar 28.

DOI:10.1007/s00417-013-2329-0
PMID:23532453
Abstract

BACKGROUND

The aim of the present study was to compare the measurement of intraocular pressure (IOP) through a therapeutic soft contact lens with the "native" measurement. We additionally investigate whether a rebound tonometer (RT) or non-contact tonometer (NCT) is more suitable to measure IOP through a bandage contact lens.

METHODS

The IOP was determined using each of the two methods, three times successively with (lens measurement) and without (native measurement) a soft contact lens. The Icare tonometer (Icare® TA01i, Icare Finland Oy, 23 subjects) and the Airpuff tonometer (Nidek NT 53OP, Nidek CO., LTD, Hiroishi Gamagori, Aichi, Japan, 16 subjects) were used. We compared the mean values (validity parameter) and standard deviation (precision parameter) of the three individual measurements in each case using the paired t-test. In addition, we conducted a power analysis to estimate the maximum error in the measurement caused by the contact lens (power level set to 0.8).

RESULTS

With the Airpuff tonometer we detected no statistically significant between the lens and the native measurement (15.6 ± 2.6 vs. 15.3 ± 2.6 mmHg; p = 0.42). The power analysis revealed that the maximum error caused by the contact lens was 1.2 mmHg. The Icare tonometry, however, trended toward higher values in the contact lens measurements (17.5 ± 4.3 vs. 16.4 ± 3.5 mmHg in the native measurements; p = 0.05). Interestingly, this difference exhibited a statistically significant correlation with the corneal thickness (0.03 mmHg per μm corneal thickness; p = 0.04).

CONCLUSION

The use of NCT and RT for IOP measurement over a soft contact lens is feasible. The accuracy appears to be sufficient for the most common clinical applications.

摘要

背景

本研究旨在比较通过治疗性软镜和“原生”测量来测量眼内压(IOP)。我们还研究了回弹眼压计(RT)或非接触眼压计(NCT)是否更适合通过绷带接触镜测量IOP。

方法

使用两种方法中的每一种,三次连续测量,一次带有(镜片测量),一次不带软接触镜(原生测量)。使用 Icare 眼压计(Icare® TA01i,Icare Finland Oy,23 例)和 Airpuff 眼压计(Nidek NT 53OP,Nidek CO.,LTD,Hiroishi Gamagori,Aichi,日本,16 例)。我们使用配对 t 检验比较了每种情况下三次单独测量的平均值(有效性参数)和标准差(精度参数)。此外,我们进行了功效分析,以估计接触镜测量引起的最大误差(设定功效水平为 0.8)。

结果

使用 Airpuff 眼压计,我们在镜片和原生测量之间未检测到统计学上的显著差异(15.6±2.6 与 15.3±2.6mmHg;p=0.42)。功效分析显示,接触镜引起的最大误差为 1.2mmHg。然而,Icare 眼压计在接触镜测量中趋于更高的值(17.5±4.3 与 16.4±3.5mmHg 的原生测量;p=0.05)。有趣的是,这种差异与角膜厚度呈统计学显著相关(每 0.03μm 角膜厚度增加 0.03mmHg;p=0.04)。

结论

使用 NCT 和 RT 通过软镜测量 IOP 是可行的。对于最常见的临床应用,其准确性似乎足够。

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