Jones I G, Sealy-Lewis H M
Department of Biochemistry, University of Hull, UK.
Curr Genet. 1989 Feb;15(2):135-42. doi: 10.1007/BF00435460.
There are at least three alcohol dehydrogenases in Aspergillus nidulans. ADHIII has no obvious physiological function. We describe here the cloning of the ADHIII gene (alcC), its mapping on linkage group VII by "reverse genetics", and the properties of multicopy transformants tested for their ability to grow on a range of alcohols (butan-1-ol being the best substrate tested for growth). We were unable to detect any obvious alteration in phenotype of a strain carrying a disrupted copy of the ADHIII gene.
构巢曲霉中至少有三种乙醇脱氢酶。ADHIII没有明显的生理功能。我们在此描述了ADHIII基因（alcC）的克隆，通过“反向遗传学”将其定位在第七连锁群上，以及对多拷贝转化体在一系列醇类（丁醇是测试生长的最佳底物）上生长能力的测试特性。我们未能检测到携带ADHIII基因破坏拷贝的菌株在表型上有任何明显变化。
