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复杂结直肠癌急诊手术中影响死亡率的因素。

Factors affecting mortality in emergency surgery in cases of complicated colorectal cancer.

作者信息

Kızıltan Remzi, Yılmaz Özkan, Aras Abbas, Çelik Sebahattin, Kotan Çetin

机构信息

School of Medicine, University of Yuzuncuyil; Department of General Surgery, Dursun Odabaş Medical Center; Van, Turkey 65090.

出版信息

Med Glas (Zenica). 2016 Feb 1;13(1):62-7. doi: 10.17392/831-16.

Abstract

AIM

To evaluate retrospectively demographic, clinical and histopathological variables effective on mortality in patients who had undergone emergency surgery due to complicated colorectal cancer.

METHODS

A total of 39 patients underwent urgent surgical interventions due to complicated colorectal cancer at the Department of General Surgery, Dursun Odabaş Medical Center, between January 2010 and January 2015. Thirty three of these were included in the study. Six patients were excluded because complete medical records had been missing. Medical records of the 33 cases were retrospectively reviewed.

RESULTS

There were 14 (42.5%) male and 19 (57.5%) female patients. Mean age was 60 years (range: 32- 83 years); 14 (42.5%) patients were less than 60 years old , while 19 (57.5%) were 60 years old or older. Operations were performed due to perforation (39.3%) and obstruction (60.6%) in 13 and 20 patients, respectively. Tumor localization was in the right and transverse colon in nine (21.2%) and in the left colon in 24 cases (72.7%). Eleven (33.3%) patients underwent resection and anastomosis, 13 (39.3%) resection and ostomy, and nine (27.2%) patients underwent ostomy alone without any resection. Postoperative mortality occurred in nine cases (27.2%).

CONCLUSIONS

High mortality should be expected in females older than 60 years with a left sided colon tumor or with another synchronous tumor and in perforated tumors. Unnecessary major resections should be avoided and primary pathology should be in the focus of treatment in order to decrease the mortality and morbidity rates.

摘要

目的

回顾性评估因复杂性结直肠癌接受急诊手术患者的人口统计学、临床和组织病理学变量对死亡率的影响。

方法

2010年1月至2015年1月期间,共有39例因复杂性结直肠癌在杜尔孙·奥达巴斯医学中心普通外科接受紧急手术干预。其中33例纳入研究。6例因完整病历缺失被排除。对33例患者的病历进行回顾性分析。

结果

男性14例(42.5%),女性19例(57.5%)。平均年龄60岁(范围:32 - 83岁);14例(42.5%)患者年龄小于60岁,19例(57.5%)患者年龄60岁及以上。分别有13例(39.3%)和20例(60.6%)因穿孔和梗阻进行手术。肿瘤位于右半结肠和横结肠9例(21.2%),位于左半结肠24例(72.7%)。11例(33.3%)患者行切除吻合术,13例(39.3%)行切除造口术,9例(27.2%)患者仅行造口术未行任何切除。9例(27.2%)患者术后死亡。

结论

60岁以上左侧结肠癌或合并其他同步肿瘤以及穿孔性肿瘤的女性患者应预期有较高死亡率。应避免不必要的大手术,治疗应聚焦于原发病理,以降低死亡率和发病率。

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