Ogunlesi Tinuade, Fetuga Bolanle, Olowonyo Michael, Adekoya Adesola, Adetola Oluseyi, Ajetunmobi Adebimpe
Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria
Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
J Trop Pediatr. 2016 Apr;62(2):107-15. doi: 10.1093/tropej/fmv083. Epub 2015 Dec 3.
This study aimed to describe the pattern and immediate outcome of severe childhood anaemia requiring blood transfusion at a secondary level of care in Nigeria. A cross-sectional survey of children hospitalized in a secondary health facility in Ogun State, Nigeria, with packed cell volume <20% and who received blood transfusion was done. Of the 253 children admitted between March 2013 and June 2014, 79 (31.2%) had severe anaemia and were transfused with blood. Two-thirds had multiple transfusions. Higher rates of blood transfusion were obtained among underweight children. Fever (98.7%), hypoglycaemia (65.8%) and tender liver (54.4%) were the leading co-morbidities. The case fatality rate was 21.5%. Respiratory distress, convulsions and altered sensorium were significantly associated with mortality. In conclusion, severe anaemia was associated with major morbidities and mortality at the secondary level of paediatric care in Nigeria.
本研究旨在描述在尼日利亚二级医疗机构中需要输血的重度儿童贫血的模式及近期转归。对尼日利亚奥贡州一家二级医疗机构中住院的血细胞比容<20%且接受输血的儿童进行了横断面调查。在2013年3月至2014年6月期间收治的253名儿童中，79名（31.2%）患有重度贫血并接受了输血。三分之二的患儿接受了多次输血。体重不足的儿童输血率更高。发热（98.7%）、低血糖（65.8%）和肝脏压痛（54.4%）是主要的合并症。病死率为21.5%。呼吸窘迫、惊厥和意识改变与死亡率显著相关。总之，在尼日利亚儿科二级护理中，重度贫血与主要合并症及死亡率相关。
