Research Center for Advanced Robotic Surgery based on Deep Tissue Imaging and Haptic Feedback Technology, Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea ; Future IT Innovation Laboratory, Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea.
Future IT Innovation Laboratory, Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea.
Photoacoustics. 2015 Aug 12;3(3):100-6. doi: 10.1016/j.pacs.2015.08.002. eCollection 2015 Sep.
We developed a near infrared (NIR) virtual intraoperative surgical photoacoustic microscopy (NIR-VISPAM) system that combines a conventional surgical microscope and an NIR light photoacoustic microscopy (PAM) system. NIR-VISPAM can simultaneously visualize PA B-scan images at a maximum display rate of 45 Hz and display enlarged microscopic images on a surgeon's view plane through the ocular lenses of the surgical microscope as augmented reality. The use of the invisible NIR light eliminated the disturbance to the surgeon's vision caused by the visible PAM excitation laser in a previous report. Further, the maximum permissible laser pulse energy at this wavelength is approximately 5 times more than that at the visible spectral range. The use of a needle-type ultrasound transducer without any water bath for acoustic coupling can enhance convenience in an intraoperative environment. We successfully guided needle and injected carbon particles in biological tissues ex vivo and in melanoma-bearing mice in vivo.
我们开发了一种近红外（NIR）虚拟术中手术光声显微镜（NIR-VISPAM）系统，该系统结合了传统手术显微镜和近红外光光声显微镜（PAM）系统。NIR-VISPAM 可以以最大显示速率 45 Hz 同时可视化 PA B 扫描图像，并通过手术显微镜的目镜将放大的显微镜图像显示在外科医生的视平面上，作为增强现实。与之前的报告中使用的可见 PAM 激发激光相比，不可见的近红外光的使用消除了对外科医生视觉的干扰。此外，该波长的最大允许激光脉冲能量大约是可见光谱范围的 5 倍。使用无需水浴进行声耦合的针式超声换能器可以提高术中环境的便利性。我们成功地在生物组织的离体和荷黑色素瘤小鼠的体内引导了针和注射了碳颗粒。
