González Eduardo G, Rancati Alberto O
1 Jefe Departamento de Mastología Instituto de Oncología "Ángel H Roffo", Universidad de Buenos Aires, Av. San Martín 5481 CABA (1427), Buenos Aires. República Argentina ; 2 Jefe Division Cirugia Oncoplastica Instituto Oncologico Henry Moore, Universidad de Buenos Aires, Argentina.
Gland Surg. 2015 Dec;4(6):541-53. doi: 10.3978/j.issn.2227-684X.2015.04.21.
The surgical treatment of breast cancer has evolved rapidly in recent decades. Conservative treatment was adopted in the late 1970s, with rates above 70%, and this was followed by a period during which the indications for surgical intervention were expanded to those patients at high risk for BRCA1, BRCA2 mutations, and also due to new staging standards and use of nuclear magnetic resonance. This increase in the indications for mastectomy coincided with the availability of immediate breast reconstruction as an oncologically safe and important surgical procedure for prevention of sequelae. Immediate reconstruction was first aimed at correcting the consequences of treatment, and almost immediately, the challenge of the technique became the achievement of a satisfactory breast appearance and shape, as well as normal consistency. The skin-sparing mastectomy (SSM) in conservation first and nipple-areola complex (NAC) later was a result of this shift that occurred from the early 1990s to the present. The objective of this review is to present all these developments specifically in relation to SSM and analyze our personal experience as well as the experience of surgeons worldwide with an emphasis on the fundamental aspects, indications, surgical technique, complications, oncological safety, and cosmetic results of this procedure.
近几十年来,乳腺癌的外科治疗发展迅速。20世纪70年代末开始采用保守治疗,其比例超过70%,随后进入一个时期,手术干预的适应症扩大到那些有BRCA1、BRCA2基因突变高风险的患者,这也是由于新的分期标准以及核磁共振的使用。乳房切除术适应症的增加与即刻乳房重建作为一种肿瘤学上安全且重要的预防后遗症的外科手术的出现相吻合。即刻重建最初旨在纠正治疗的后果,几乎紧接着,该技术面临的挑战就变成了实现令人满意的乳房外观、形状以及正常的质地。先进行保留皮肤的乳房切除术(SSM),之后再切除乳头乳晕复合体(NAC),这是从20世纪90年代初至今所发生的这种转变的结果。本综述的目的是专门介绍所有这些与SSM相关的进展,并分析我们个人的经验以及全球外科医生的经验,重点关注该手术的基本方面、适应症、手术技术、并发症、肿瘤学安全性和美容效果。