Ehling U H
GSF-Institut für Säugetiergenetik, Neuherberg.
Naturwissenschaften. 1989 May;76(5):194-9. doi: 10.1007/BF00627685.
Associated with technical advances of our civilization is the possibility of an increase of radiation- and chemically induced germ-cell mutations in man. This would result in an increase in the frequency of genetic diseases and would be detrimental to future generations. It is the duty of our generation to keep this risk as low as possible. In order to achieve this goal it is necessary to identify, evaluate and quantify the genetic risk of chemical mutagens. The possibilities and the shortcomings of the quantification of radiation- and chemically induced mutations are discussed. The discrepancy between the high safety standards for radiation protection and the low level of knowledge for the toxicological evaluation of chemicals is emphasized.
伴随我们文明的技术进步而来的是，人类中由辐射和化学物质诱发的生殖细胞突变有可能增加。这将导致遗传疾病的发生率上升，并对后代产生不利影响。我们这一代人有责任将这种风险降至最低。为了实现这一目标，有必要识别、评估和量化化学诱变剂的遗传风险。文中讨论了量化辐射和化学物质诱发突变的可能性及不足之处。强调了辐射防护的高安全标准与化学品毒理学评估知识水平较低之间的差异。
