Schober R, Sundmacher R, Schirmer M, Wechsler W
Department of Neuropathology, University of Düsseldorf, West Germany.
Neurosurg Rev. 1989;12(1):63-6. doi: 10.1007/BF01787132.
A case of primary malignant lymphoma of the brain with preceding first unilateral, then bilateral uveitis and retinochorioiditis is presented. The diagnosis was established on brain biopsy material using immuno-histochemical methods. The autopsy disclosed a polymorphous immunocytoma with bilateral brain involvement including structures of the posterior optic pathways. Clinical and pathogenetic implications regarding this "oculo-cerebral type" of malignant lymphoma, which has been only seldom reported in the literature are discussed.
本文报告一例原发性脑恶性淋巴瘤病例,该病例先出现单侧葡萄膜炎,后发展为双侧葡萄膜炎及视网膜脉络膜炎。通过免疫组织化学方法对脑活检材料进行检测以明确诊断。尸检发现多形性免疫细胞瘤,双侧脑均受累,包括视路后部结构。本文讨论了这种“眼脑型”恶性淋巴瘤的临床及发病机制意义,该类型在文献中鲜有报道。