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以眼科症状为表现的原发性颅内恶性淋巴瘤:活检及尸检病例研究

Primary intracerebral malignant lymphoma presenting with ophthalmological symptoms: bioptical and autoptical case study.

作者信息

Schober R, Sundmacher R, Schirmer M, Wechsler W

机构信息

Department of Neuropathology, University of Düsseldorf, West Germany.

出版信息

Neurosurg Rev. 1989;12(1):63-6. doi: 10.1007/BF01787132.

DOI:10.1007/BF01787132
PMID:2664557
Abstract

A case of primary malignant lymphoma of the brain with preceding first unilateral, then bilateral uveitis and retinochorioiditis is presented. The diagnosis was established on brain biopsy material using immuno-histochemical methods. The autopsy disclosed a polymorphous immunocytoma with bilateral brain involvement including structures of the posterior optic pathways. Clinical and pathogenetic implications regarding this "oculo-cerebral type" of malignant lymphoma, which has been only seldom reported in the literature are discussed.

摘要

本文报告一例原发性脑恶性淋巴瘤病例,该病例先出现单侧葡萄膜炎,后发展为双侧葡萄膜炎及视网膜脉络膜炎。通过免疫组织化学方法对脑活检材料进行检测以明确诊断。尸检发现多形性免疫细胞瘤,双侧脑均受累,包括视路后部结构。本文讨论了这种“眼脑型”恶性淋巴瘤的临床及发病机制意义,该类型在文献中鲜有报道。

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Primary intracerebral malignant lymphoma presenting with ophthalmological symptoms: bioptical and autoptical case study.以眼科症状为表现的原发性颅内恶性淋巴瘤:活检及尸检病例研究
Neurosurg Rev. 1989;12(1):63-6. doi: 10.1007/BF01787132.
2
[Primary retinocerebral reticulosaromatosis (anatomo-clinical case report)].
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3
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Arch Ophthalmol. 1979 Aug;97(8):1505-7. doi: 10.1001/archopht.1979.01020020167016.
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本文引用的文献

1
[Primary reticuloendotheliosis of the brain, with special reference to a peculiar, hitherto unknown granulomatous process in the brain].[脑原发性网状内皮细胞增多症,特别提及大脑中一种特殊的、迄今未知的肉芽肿性病变]
Dtsch Z Nervenheilkd. 1950;164(4):332-80.
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Nervenarzt. 1956 Jun 20;27(6):244-51.
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Combined malignant lymphoma of the eye and CNS (reticulum-cell sarcoma). Report of three cases.
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4
Uveitis associated with isolated reticulum cell sarcoma of the brain.与孤立性脑网状细胞肉瘤相关的葡萄膜炎。
Am J Ophthalmol. 1972 Mar;73(3):431-6. doi: 10.1016/0002-9394(72)90072-4.
5
Computer-assisted stereotaxic biopsy for the diagnosis of primary central nervous system lymphoma.计算机辅助立体定向活检用于原发性中枢神经系统淋巴瘤的诊断。
Neurology. 1987 Jul;37(7):1160-4. doi: 10.1212/wnl.37.7.1160.
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Primary malignant lymphoma of the brain: an immunohistochemical study of eight cases using a panel of monoclonal and heterologous antibodies.
Acta Neuropathol. 1986;71(3-4):190-6. doi: 10.1007/BF00688039.
7
Vitreous cellular reaction. Association with reticulum cell sarcoma of brain.
Arch Ophthalmol. 1975 Dec;93(12):1341-5. doi: 10.1001/archopht.1975.01010020967006.
8
Posterior uveitis and primary cerebral reticulum cell sarcoma.后葡萄膜炎与原发性脑网状细胞肉瘤
Arch Ophthalmol. 1975 Feb;93(2):123-4. doi: 10.1001/archopht.1975.01010020129006.
9
Ocular reticulum cell sarcoma.眼网状细胞肉瘤
Am J Ophthalmol. 1975 Jan;79(1):39-47. doi: 10.1016/0002-9394(75)90453-5.
10
["Primary" reticulum-cellsarcoma of the retina. I. Clinico-pathologic study of 5 patients (author's transl)].视网膜“原发性”网状细胞肉瘤。I. 5例患者的临床病理研究(作者译)
Klin Monbl Augenheilkd. 1977 Oct;171(4):489-99.